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Process of cerebral edema in the infarct core after reperfusion: A case report

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机构: [1]Department of Neurology, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China, [2]The Second School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
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关键词: cerebral edema cerebral infarction hypoattenuation reperfusion

摘要:
Rationale: It is generally believed that cerebral infarction shows hypoattenuation on computed tomography (CT) scans 12 to 24 hours after onset. Cerebral edema affects the occurrence of hypoattenuation, originating from the inner edge of the infarct and extending to the core. When reperfusion occurs in the infarct, the process of cerebral edema changes significantly, affecting the imaging of cerebral infarction on CT scans. This article focused on the mechanism of cerebral edema to provide a new perspective for understanding the impact of reperfusion on cerebral infarction. Patient concerns: We describe the case of a 77-year-old man who presented with an acute onset of right limb weakness with speech difficulties 10 hours before the visit. He had been diagnosed with atrial fibrillation 4 months ago. During the acute phase of infarction, the central area of the hypoattenuated infarct appears as isodensity on CT scans in this case. Diagnoses: The patient was diagnosed with acute cerebral infarction, cardiogenic cerebral embolism, and spontaneous recanalization of left middle cerebral artery occlusion. Interventions: Metoprolol was given to control the ventricular rate. The patient received blood pressure control, symptomatic management, and rehabilitation treatments. Outcomes: Finally, the patient became alert. Lessons: Cerebral edema originating directly in the infarct core after reperfusion could lead to a significantly accelerated edema process and imaging evolution, causing more severe cerebral damage. In such a case, the patient should not receive antiplatelet and anticoagulant therapy in order to prevent bleeding conversion.

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出版当年[2021]版:
大类 | 4 区 医学
小类 | 4 区 医学:内科
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 医学:内科
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出版当年[2020]版:
Q3 MEDICINE, GENERAL & INTERNAL
最新[2023]版:
Q2 MEDICINE, GENERAL & INTERNAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2020版] 出版当年五年平均 出版前一年[2019版] 出版后一年[2021版]

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第一作者机构: [1]Department of Neurology, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China,
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通讯机构: [1]Department of Neurology, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China, [2]The Second School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China. [*1]The Second School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510120, China
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