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Recognition of Freezing of Gait in Parkinson's Disease Based on Machine Vision

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机构: [1]Department of Neurosurgery, General Hospital of Southern Theater Command of PLA, Guangzhou, China. [2]Graduate School, Guangzhou University of Chinese Medicine, Guangzhou, China. [3]GYENNO SCIENCE Co., LTD., Shenzhen, China. [4]Department of Neurology, The 960th Hospital of PLA, Taian, China. [5]Department of Neurosurgery, Guangdong Second Provincial General Hospital, Guangzhou, China. [6]Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [7]Department of Neurology, Guangzhou First People's Hospital, Guangzhou, China. [8]HUST-GYENNO CNS Intelligent Digital Medicine Technology Center, Wuhan, China. [9]Branch of National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Guangzhou, China.
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Freezing of gait (FOG) is a common clinical manifestation of Parkinson's disease (PD), mostly occurring in the intermediate and advanced stages. FOG is likely to cause patients to fall, resulting in fractures, disabilities and even death. Currently, the pathogenesis of FOG is unclear, and FOG detection and screening methods have various defects, including subjectivity, inconvenience, and high cost. Due to limited public healthcare and transportation resources during the COVID-19 pandemic, there are greater inconveniences for PD patients who need diagnosis and treatment.A method was established to automatically recognize FOG in PD patients through videos taken by mobile phone, which is time-saving, labor-saving, and low-cost for daily use, which may overcome the above defects. In the future, PD patients can undergo FOG assessment at any time in the home rather than in the hospital.In this study, motion features were extracted from timed up and go (TUG) test and the narrow TUG (Narrow) test videos of 50 FOG-PD subjects through a machine learning method; then a motion recognition model to distinguish between walking and turning stages and a model to recognize FOG in these stages were constructed using the XGBoost algorithm. Finally, we combined these three models to form a multi-stage FOG recognition model.We adopted the leave-one-subject-out (LOSO) method to evaluate model performance, and the multi-stage FOG recognition model achieved a sensitivity of 87.5% sensitivity and a specificity of 79.82%.A method to realize remote PD patient FOG recognition based on mobile phone video is presented in this paper. This method is convenient with high recognition accuracy and can be used to rapidly evaluate FOG in the home environment and remotely manage FOG-PD, or screen patients in large-scale communities.Copyright © 2022 Li, Chen, Zhang, Lu, Zhang, Bai, Liang, Wang, Du, Xue, Ling, Ren, Zou, Chen, Li, Chen and Zou.

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出版当年[2021]版:
大类 | 2 区 医学
小类 | 2 区 老年医学 3 区 神经科学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 老年医学 3 区 神经科学
第一作者:
第一作者机构: [1]Department of Neurosurgery, General Hospital of Southern Theater Command of PLA, Guangzhou, China. [2]Graduate School, Guangzhou University of Chinese Medicine, Guangzhou, China.
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通讯机构: [1]Department of Neurosurgery, General Hospital of Southern Theater Command of PLA, Guangzhou, China. [3]GYENNO SCIENCE Co., LTD., Shenzhen, China. [8]HUST-GYENNO CNS Intelligent Digital Medicine Technology Center, Wuhan, China. [9]Branch of National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Guangzhou, China.
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