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An overview of Twist1 in glioma progression and recurrence

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WOS体系：
Pubmed体系：
作者：
Li Cong[1,2] * ; Li Zixuan[2] ; Zhang Mengyi[2] ; Dai Jiaxuan[2] ; Wang Yunmin[3] ; Zhang Zhiqiang[1,2] ;
机构： [1]The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Province Hospital of Chinese Medicine, Guangzhou, Guangdong Province, P.R. China [2]The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, P.R. China [3]The Jining City Center Blood Station, Jining, Shandong Province, P.R. China
出处：
DOI： 10.1016/bs.irn.2023.07.003
ISSN：

摘要：
Glioma cells are characterized by high migration ability, resulting in the aggressive growth of the tumors and poor prognosis of patients. Epithelial-to-mesenchymal transition (EMT) is one of the most important steps for tumor migration and metastasis and be elevated during glioma progression and recurrence. Twist1 is a basic helix-loop-helix transcription factor and a key transcription factor involved in the process of EMT. Twist1 is related to glioma mesenchymal change, invasion, heterogeneity, self-renewal of tumor stem cells, angiogenesis, etc., and may be used as a prognostic indicator and therapeutic target for glioma patients. This paper mainly reviews the structural characteristics, regulatory mechanisms, and apparent regulation of Twist1, as well as the roles of Twist1 during glioma progression and recurrence, providing new revelations for its use as a potential drug target and glioma treatment research.Copyright © 2023. Published by Elsevier Inc.

基金：
This work was supported by the 13th Zhaoyang Talent Plan of Guangdong Province Hospital of Chinese Medicine (No. ZY2022YL11) and Special project of Guangdong Province Hospital of Chinese Medicine (No. YN2020QN06).
语种：
外文
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PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类 | 3 区 医学
小类 | 4 区 神经科学
最新[2025]版：
无
第一作者：
第一作者机构： [1]The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Province Hospital of Chinese Medicine, Guangzhou, Guangdong Province, P.R. China [2]The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, P.R. China
通讯作者：
通讯机构： [1]The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Province Hospital of Chinese Medicine, Guangzhou, Guangdong Province, P.R. China [2]The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, P.R. China
推荐引用方式(GB/T 7714)：
Li Cong,Li Zixuan,Zhang Mengyi,et al.An overview of Twist1 in glioma progression and recurrence[J].International review of neurobiology.2023,172:285-301.doi:10.1016/bs.irn.2023.07.003.
APA：
Li Cong,Li Zixuan,Zhang Mengyi,Dai Jiaxuan,Wang Yunmin&Zhang Zhiqiang.(2023).An overview of Twist1 in glioma progression and recurrence.International review of neurobiology,172,
MLA：
Li Cong,et al."An overview of Twist1 in glioma progression and recurrence".International review of neurobiology 172.(2023):285-301

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