机构：[1]College of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.[2]National Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Jiangsu Kanion Pharmaceutical Co. Ltd, Lianyungang, Jiangsu, China.[3]Preventive Medicine Department, Lianyungang Hospital of T CM Affiliated to Nanjing University of Chinese Medicine, Lianyungang, China.
Two undescribed sesquiterpenoids, including one nor-eudesmane type (1) and one guaiane type (2), together with two known analogues (3-4) have been isolated and identified from the fruits of Alpinia oxyphylla. The structures of these new compounds were elucidated by extensive spectroscopic analyses (1D-, 2D-NMR, HRESIMS, IR, UV) and NMR calculations with DP4+ analysis. The anti-inflammatory activities of all isolates were evaluated by measuring their inhibitory effects on PGE2 production in LPS stimulated RAW 264.7 macrophages.
基金：
This work was supported by grants from the Programs Foundation for Leading Talents in National Administration of Traditional Chinese Medicine of China “Qihuang scholars” Project
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类|3 区化学
小类|3 区应用化学4 区药物化学
最新[2025]版：
大类|3 区化学
小类|3 区应用化学4 区药物化学
第一作者：
第一作者机构：[1]College of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.[2]National Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Jiangsu Kanion Pharmaceutical Co. Ltd, Lianyungang, Jiangsu, China.
共同第一作者：
通讯作者：
通讯机构：[1]College of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.[2]National Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Jiangsu Kanion Pharmaceutical Co. Ltd, Lianyungang, Jiangsu, China.
推荐引用方式(GB/T 7714)：
Bai Weirong,Wang Tuanjie,Yang Xiaoming,et al.Two new sesquiterpenoids from the fruits of Alpinia oxyphylla[J].Natural product research.2023,1-7.doi:10.1080/14786419.2023.2272282.
APA：
Bai Weirong,Wang Tuanjie,Yang Xiaoming,Wang Zhenzhong,Li Haibo&Geng Jianliang.(2023).Two new sesquiterpenoids from the fruits of Alpinia oxyphylla.Natural product research,,
MLA：
Bai Weirong,et al."Two new sesquiterpenoids from the fruits of Alpinia oxyphylla".Natural product research .(2023):1-7
