Association between dietary carotenoid intakes and abdominal aortic calcification in adults: National Health and Nutrition Examination Survey 2013-2014
Objective Abdominal aortic calcification (AAC) is an important marker of subclinical atherosclerosis and a predictor of cardiovascular disease. This study aims to explore the association between carotenoid intakes and AAC. Methods We included 2889 participants from the National Health and Nutrition Examination Survey (NHANES). Dietary carotenoid intakes were obtained through 24-h dietary recall interviews. Severe AAC was defined as a Kauppila score > 5. The main analysis utilizes logistic and restricted cubic spline models. Result Severe AAC was detected in 378 (13.08%) participants. In fully adjusted models, the odds ratios (OR) with 95% confidence intervals (CI) of alpha-carotene, beta-carotene, beta-cryptoxanthin, lycopene, lutein with zeaxanthin and total carotenoid intakes for individuals with severe AAC were 0.53 (0.23-0.77), 0.39 (0.19-0.80), 0.18 (0.05-0.62), 0.40 (0.20-0.78), 0.53 (0.32-0.88) and 0.38 (0.18-0.77) in the highest versus lowest quartile intake, respectively. Dose-response analyses revealed that all of the carotenoids were associated with decreased risk of severe AAC in a nonlinear trend. Total carotenoid intakes of at least 100ug/kg/day were associated with decreased odds for severe AAC. Conclusion alpha-carotene, beta-carotene, beta-cryptoxanthin, lycopene, lutein with zeaxanthin and total carotenoids were inversely associated with the risk of severe AAC in adults.
基金：
Guangzhou University of Chinese Medicine Discipline High-Quality Enhancement Project - Functional Assessment and Risk Warning of Traditional Chinese Medicine for Disease Prevention; State Key Laboratory of Dampness Syndrome of Chinese Medicine; Second Affiliated Hospital of Guangzhou University of Chinese Medicine; Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine [SZ2021ZZ32]; Science and Technology Planning Project of Guangdong Province [2023B1212060063]; Self-Funded Science and Technology Innovation Project in Foshan City; Sixth Affiliated Hospital of South China University of Technology [232001007374]
语种：
外文
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2023]版：
大类|3 区医学
小类|3 区环境科学3 区公共卫生、环境卫生与职业卫生
最新[2025]版：
大类|3 区医学
小类|3 区环境科学3 区公共卫生、环境卫生与职业卫生
JCR分区：
出版当年[2022]版：
Q4ENVIRONMENTAL SCIENCESQ4PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
第一作者机构：[1]Guangzhou Univ Chinese Med, Clin Med Coll 2, 111,Dade Rd, Guangzhou 510120, Peoples R China[2]South China Univ Technol, Affiliated Hosp 6, Sch Med, Dept Integrated Tradit Chinese & Western Med Nutr, Foshan 528225, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Chen Weidong,Li Yuanqing,Li Min,et al.Association between dietary carotenoid intakes and abdominal aortic calcification in adults: National Health and Nutrition Examination Survey 2013-2014[J].JOURNAL OF HEALTH POPULATION AND NUTRITION.2024,43(1):doi:10.1186/s41043-024-00511-9.
APA：
Chen, Weidong,Li, Yuanqing,Li, Min,Li, Hai,Chen, Caifang&Lin, Yanzhao.(2024).Association between dietary carotenoid intakes and abdominal aortic calcification in adults: National Health and Nutrition Examination Survey 2013-2014.JOURNAL OF HEALTH POPULATION AND NUTRITION,43,(1)
MLA：
Chen, Weidong,et al."Association between dietary carotenoid intakes and abdominal aortic calcification in adults: National Health and Nutrition Examination Survey 2013-2014".JOURNAL OF HEALTH POPULATION AND NUTRITION 43..1(2024)
