Objective:To analyze TCM Master WANG Qi's medication rules on treatment of insomnia by cluster statistical method.Methods:Effective or cured cases of insomnia in Professor WANG Qi's outpatient clinic were selected and analyzed with EXCEL to count the frequency of used Chinese Medicine prescription,which includes the number,the frequency and the cumulative frequency of herbs.Herbs that had been used with over 91.23％ cumulative frequency (the number exceed 10) were taken as highly frequently used herbs and cluster analysis was conducted using soft-ware SPSS 20.0 to analyze them.Results:We assembled 223 cases of patients that involve 297 cases of Chinese Medicine prescriptions.And there were altogether 181 Chinese Medicine herbs,among which 62 were highly frequently used herbs.The six clustering prescriptions were concluded and analyzed basing on the efficacy of herbs.Conclusion:In clustering square analysis on WANG Qi's proven case,GaozhenWuyou decoction （高枕无忧汤） is highly frequent formula.Professor WANG Qi highlights the principal causes and symptoms as well as physique differentiation,and adept in the treatment of insomnia from liver and blood stasis.