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Differences in serum proteins in traditional Chinese medicine constitutional population: Analysis and verification

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机构: [1]State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China [2]Guangzhou University of Chinese Medicine, Second Clinical Medicine Collage, Guangzhou, China [3]South China Biochip Research Center, Guangzhou, China [4]RayBiotech, Inc., Guangzhou, China [5]The 8th People’s Hospital of Nanhai District, Foshan, China [6]The Fourth People’s Hospital of Nanhai District of Foshan City, Foshan, China [7]Xiqiao town Community Health Service Center, Foshan, China [8]RayBiotech Life, Inc., Peachtree Corners, Georgia, USA
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关键词: antibody microarray balanced constitution classification model constitution transformation dampness constitution

摘要:
Traditional Chinese medicine assigns individuals into different categories called "constitutions" to help guide the clinical treatment according to subjective physiologic, psychologic analyses, large-scale clinical observations, and epidemiologic studies. To further explore more objective expressions of constitutions, antibody microarrays were used to analyze the serologic protein profiles of two different constitutions, a balanced (or healthy) constitution (BC) and the dampness constitution (DC) comprising phlegm-dampness and damp-heat constitutions. The profiles of changing constitutions across time were also analyzed. Nineteen differentially expressed proteins between the two groups were identified, with known biologic functions involved in immunity and inflammation. This proteomic study may provide a biologic explanation why the BC is different than the dampness constitution.

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出版当年[2019]版:
大类 | 2 区 医学
小类 | 3 区 细胞生物学 3 区 血液学 3 区 免疫学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 细胞生物学 4 区 血液学 4 区 免疫学
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出版当年[2018]版:
Q2 HEMATOLOGY Q2 CELL BIOLOGY Q2 IMMUNOLOGY
最新[2023]版:
Q2 HEMATOLOGY Q2 IMMUNOLOGY Q3 CELL BIOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2018版] 出版当年五年平均 出版前一年[2017版] 出版后一年[2019版]

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第一作者机构: [1]State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China [2]Guangzhou University of Chinese Medicine, Second Clinical Medicine Collage, Guangzhou, China
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通讯机构: [1]State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China [2]Guangzhou University of Chinese Medicine, Second Clinical Medicine Collage, Guangzhou, China [3]South China Biochip Research Center, Guangzhou, China [4]RayBiotech, Inc., Guangzhou, China [8]RayBiotech Life, Inc., Peachtree Corners, Georgia, USA [*1]StateKey Laboratory ofDampness Syndrome of Chinese Medicine, The Second Affiliated Hospital ofGuangzhou University of Chinese Medicine. No. 111 Dade Road,Guangzhou 510120,P. R. China [*2]RayBiotech Life, Inc., 3607 Parkway Lane, Suite 200,Peachtree Corners,GA 30092,USA
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