机构:[1]State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China广东省中医院[2]Guangzhou University of Chinese Medicine, Second Clinical Medicine Collage, Guangzhou, China广东省中医院[3]South China Biochip Research Center, Guangzhou, China[4]RayBiotech, Inc., Guangzhou, China[5]The 8th People’s Hospital of Nanhai District, Foshan, China[6]The Fourth People’s Hospital of Nanhai District of Foshan City, Foshan, China[7]Xiqiao town Community Health Service Center, Foshan, China[8]RayBiotech Life, Inc., Peachtree Corners, Georgia, USA
Traditional Chinese medicine assigns individuals into different categories called "constitutions" to help guide the clinical treatment according to subjective physiologic, psychologic analyses, large-scale clinical observations, and epidemiologic studies. To further explore more objective expressions of constitutions, antibody microarrays were used to analyze the serologic protein profiles of two different constitutions, a balanced (or healthy) constitution (BC) and the dampness constitution (DC) comprising phlegm-dampness and damp-heat constitutions. The profiles of changing constitutions across time were also analyzed. Nineteen differentially expressed proteins between the two groups were identified, with known biologic functions involved in immunity and inflammation. This proteomic study may provide a biologic explanation why the BC is different than the dampness constitution.
基金:
Foundation of Guangdong Provincial Hospital of Traditional Chinese Medicine [YN2018RBA01, YN2018DB02]; RayBiotech Innovative Research Fund, Guangzhou Innovation Leadership Team [CXLJTD-201602]; Guangzhou Pearl River Nova Program [201806010035, 201806010032]; Guangdong Province Key Technologies R&D Program for "Precision Medicine and Stem Cells" [2019B020231002, 2019B020227004]; 2018 National Key Technologies R&D Program for "Prevention and treatment of Major Infectious Diseases such as AIDS and Viral Hepatitis" [2018ZX10732401]; Industry-University-Research Collaborative Innovation Special Project of Guangzhou, China [201802030001]
第一作者机构:[1]State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China[2]Guangzhou University of Chinese Medicine, Second Clinical Medicine Collage, Guangzhou, China
共同第一作者:
通讯作者:
通讯机构:[1]State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China[2]Guangzhou University of Chinese Medicine, Second Clinical Medicine Collage, Guangzhou, China[3]South China Biochip Research Center, Guangzhou, China[4]RayBiotech, Inc., Guangzhou, China[8]RayBiotech Life, Inc., Peachtree Corners, Georgia, USA[*1]StateKey Laboratory ofDampness Syndrome of Chinese Medicine, The Second Affiliated Hospital ofGuangzhou University of Chinese Medicine. No. 111 Dade Road,Guangzhou 510120,P. R. China[*2]RayBiotech Life, Inc., 3607 Parkway Lane, Suite 200,Peachtree Corners,GA 30092,USA
推荐引用方式(GB/T 7714):
Fei Tan,Xinyan Chen,Huihua Zhang,et al.Differences in serum proteins in traditional Chinese medicine constitutional population: Analysis and verification[J].JOURNAL OF LEUKOCYTE BIOLOGY.2020,108(2):547-557.doi:10.1002/JLB.6VMA0220-663RR.
APA:
Fei Tan,Xinyan Chen,Huihua Zhang,Jiamin Yuan,Chen Sun...&Zhimin Yang.(2020).Differences in serum proteins in traditional Chinese medicine constitutional population: Analysis and verification.JOURNAL OF LEUKOCYTE BIOLOGY,108,(2)
MLA:
Fei Tan,et al."Differences in serum proteins in traditional Chinese medicine constitutional population: Analysis and verification".JOURNAL OF LEUKOCYTE BIOLOGY 108..2(2020):547-557