机构：[1]Department of Gastroenterology, Tongde Hospital of Zhejiang Province, Hangzhou 310012, China [2]Guangzhou University of Chinese Medicine, Guangzhou 510405, China 深圳市中医院深圳医学信息中心[3]The Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China [4]The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510000, China广东省中医院深圳市中医院深圳医学信息中心
Gastric precancerous lesions (GPLs) are an essential precursor in the occurrence and development of gastric cancer, known to be one of the most common and lethal cancers worldwide. Traditional Chinese medicine (TCM) has a positive prospect for the prevention and therapy of GPL owing to several advantages including a definite curative effect, fewer side effects compared to other treatments, multiple components, and holistic regulation. Despite these characteristic advantages, the mechanisms of TCM in treating GPL have not been fully elucidated. In this review, we summarize the current knowledge with respect to herbal formulations and the therapeutic mechanisms of TCM active ingredients for GPL. This paper elaborates on the mechanisms of TCM underlying the prevention and treatment of GPL, specifically those that are linked to anti-H. pylori, anti-inflammation, antiproliferation, proapoptotic, antioxidation, antiglycolytic, and antiangiogenesis effects.
基金：
13th Five-Year Plan of Zhejiang Provincial Key Discipline Construction of Traditional Chinese Medicine [2017-XK-B02]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81673946, 81973816]; Characteristic Innovation Projects of Colleges and Universities in Guangdong Province [2018KTSCX040]; Guangzhou Science and Technology Plan Project [201803010055]
第一作者机构：[1]Department of Gastroenterology, Tongde Hospital of Zhejiang Province, Hangzhou 310012, China [2]Guangzhou University of Chinese Medicine, Guangzhou 510405, China
通讯作者：
推荐引用方式(GB/T 7714)：
Yang Liangjun,Li Jiali,Hu Zhipeng,et al.A Systematic Review of the Mechanisms Underlying Treatment of Gastric Precancerous Lesions by Traditional Chinese Medicine[J].EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE.2020,2020:doi:10.1155/2020/9154738.
APA：
Yang, Liangjun,Li, Jiali,Hu, Zhipeng,Fan, Xiangzhen,Cai, Tiantian...&Pan, Huafeng.(2020).A Systematic Review of the Mechanisms Underlying Treatment of Gastric Precancerous Lesions by Traditional Chinese Medicine.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2020,
MLA：
Yang, Liangjun,et al."A Systematic Review of the Mechanisms Underlying Treatment of Gastric Precancerous Lesions by Traditional Chinese Medicine".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2020.(2020)
