机构：[1]Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing 100853, China[2]Department of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai 200433, China[3]Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China首都医科大学附属北京友谊医院[4]Department of Gastroenterology and Hepatology, Sichuan Cancer Hospital and Institute, Chengdu 610000, Sichuan Province, China四川省肿瘤医院[5]Department of Gastroenterology, First Affiliated Hospital of School of Medicine, Shihezi University, Shihezi 832002, Xinjiang Uygur Autonomous Region, China[6]Department of Surgery, Prince of Wales Hospital, the Chinese University of Hong Kong, Hong Kong, China[7]Department of Gastroenterology, the Second Affiliated Hospital of Baotou Medical College, Baotou 014030, Inner Mongolia Autonomous Region, China内蒙古科技大学包头医学院[8]Department of Gastroenterology, Shenzhen Hospital of Southern Medical University, Shenzhen 518000, Guangdong Province, China南方医科大学深圳医院深圳市康宁医院深圳医学信息中心[9]Gastrointestinal Endoscopy Center, Affiliated Hospital of Nanjing Traditional Chinese Medicine University, Nanjing 210029, Jiangsu Province, China[10]Department of Gastroenterology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China北京朝阳医院[11]Department of Gastroenterology, the First Affiliated Hospital of Xi’an Jiao Tong University, Xi’an 710000, Shaanxi Province, China[12]Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China四川大学华西医院[13]Department of Endoscopy, Eastern Hepatobiliary Surgical Hospital Affiliated to Naval Medical University, Shanghai 200438, China[14]Department of Gastroenterology, the Second Hospital of Lanzhou University,Lanzhou 730030, Gansu Province, China[15]Department of Gastroenterology, Peking University Third Hospital, Beijing 100191, China[16]Division of Gastroenterology and Hepatology, the Johns Hopkins University School of Medicine, Baltimore, MD 21218, United States[17]Department of Gastrointestinal Endoscopy, Prince of Wales Hospital, the Chinese University of Hong Kong, Hong Kong, China[18]Department of Gastroenterology, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China[19]Department of Gastroenterology, Second Xiangya Hospital of Central South University, Changsha 410000, Hunan Province, China[20]Department of Gastroenterology, General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China[21]Division of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China华中科技大学同济医学院附属协和医院[22]Department of Gastroenterology, Sichuan Provincial People’s Hospital, Chengdu 610072, Sichuan Province, China四川省人民医院[23]Department of Gastroenterology, Xijing Hospital, Air Force Medical University, Xi’an 710032, Shaanxi Province, China[24]Department of Digestion, Qinghai Provincial People’s Hospital, Xining 810007, Qinghai Province, China[25]Department of Gastroenterology, Southwest Hospital, Army Medical University, Chongqing 400038, China[26]Department of Gastroenterology, Peking University First Hospital, Beijing 100034, China[27]Department of Gastroenterology and Hepatology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong Province, China广东省人民医院[28]Department of Gastroenterology, Beijing Military General Hospital, Beijing 100700, China[29]Endoscopy Center, the Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China[30]Endoscopy Center, Shengjing Hospital, China Medical University, Shenyang 110004, Liaoning Province, China中国医科大学附属盛京医院[32]National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100020, China[33]Department of General Surgery, Fuzhou General Hospital, Fuzhou 350025, Fujian Province, China[34]Endoscopy Center, Peking University Cancer Hospital and Institute, Beijing 100142, China[35]Endoscopy Center, the First Hospital of Jilin University, Changchun 130021, Jilin Province, China[36]Ping-Hong Zhou, Endoscopy Center, Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China[37]Department of Gastroenterology, Peking Union Medical College Hospital, Beijing 100730, China[38]Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan University, Wuhan 430060, Hubei Province, China[39]Endoscopy Center, China-Japan Union Hospital of Jilin University, Changchun 130021, Jilin Province, China吉林大学中日联谊医院[40]Department of Gastroenterology, Hangzhou First People’s Hospital, Hangzhou 310006, Zhejiang Province, China
With the digestive endoscopic tunnel technique (DETT), many diseases that previously would have been treated by surgery are now endoscopically curable by establishing a submucosal tunnel between the mucosa and muscularis propria (MP). Through the tunnel, endoscopic diagnosis or treatment is performed for lesions in the mucosa, in the MP, and even outside the gastrointestinal (GI) tract. At present, the tunnel technique application range covers the following: (1) Treatment of lesions originating from the mucosal layer, e.g., endoscopic submucosal tunnel dissection for oesophageal large or circular early-stage cancer or precancerosis; (2) treatment of lesions from the MP layer, per-oral endoscopic myotomy, submucosal tunnelling endoscopic resection, etc.; and (3) diagnosis and treatment of lesions outside the GI tract, such as resection of lymph nodes and benign tumour excision in the mediastinum or abdominal cavity. With the increasing number of DETTs performed worldwide, endoscopic tunnel therapeutics, which is based on DETT, has been gradually developed and optimized. However, there is not yet an expert consensus on DETT to regulate its indications, contraindications, surgical procedure, and postoperative treatment. The international DEI'l Alliance signed up this consensus to standardize the procedures of DETT. In this consensus, we describe the definition, mechanism, and significance of DETT, prevention of infection and concepts of DETT-associated complications, methods to establish a submucosal tunnel, and application of DETT for lesions in the mucosa, in the MP and outside the GI tract (indications and contraindications, procedures, pre- and postoperative treatments, effectiveness, complications and treatments, and a comparison between DETT and other operations).
基金：
National Key R and D Program of China [2016YFC1303601]
第一作者机构：[1]Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing 100853, China
通讯作者：
通讯机构：[1]Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing 100853, China[*1]Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing 100853, China.
推荐引用方式(GB/T 7714)：
Ning-Li Chai,Hui-Kai Li,En-Qiang Linghu,et al.Consensus on the digestive endoscopic tunnel technique[J].WORLD JOURNAL OF GASTROENTEROLOGY.2019,25(7):744-776.doi:10.3748/wjg.v25.i7.744.
APA：
Ning-Li Chai,Hui-Kai Li,En-Qiang Linghu,Ya-Qi Zhai,Zhao-Shen Li...&Xiao-Feng Zhang.(2019).Consensus on the digestive endoscopic tunnel technique.WORLD JOURNAL OF GASTROENTEROLOGY,25,(7)
MLA：
Ning-Li Chai,et al."Consensus on the digestive endoscopic tunnel technique".WORLD JOURNAL OF GASTROENTEROLOGY 25..7(2019):744-776
