机构：[1]Evidence-based Medicine and Clinical research Service Group, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China广东省中医院[2]Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China广东省中医院[3]The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China广东省中医院[4]China-Australia International Research Centre for Chinese Medicine, School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia
Introduction The aim of this systematic review is to assess the efficacy and safety of Chinese herbal medicine for the treatment of patients with vascular cognitive impairment but no dementia. Methods and analysis We will perform a comprehensive retrieval in the following electronic databases: PubMed, Cochrane Library, EMBASE, CINAHL, Chinese Biomedical Literature Service System (SinoMed), China National Knowledge Infrastructure (CNKI), Chinese Scientific Journals Database (VIP), Wan-fang database and other sources. After screening the studies, the methodological quality of all included trials will be assessed according to the risk of bias instrument provided by the Cochrane Collaboration. A meta-analysis of randomised controlled trials will be conducted using RevMan V.5.3 software. Funnel plot analysis and Egger's test will be used to assess publication bias, if possible. The quality of evidence will be assessed by the GRADE system. Dissemination This systematic review will be disseminated in a peer-reviewed journal and a relevant conference presentation. Trial registration number PROSPERO CRD 42015023682.
基金：
Guangdong Provincial Science & Technology Department; Guangdong Provincial Academy of Chinese Medical Sciences (GPACMS) [2012A032500009]; International Science & Technology Cooperation Project of the Ministry of Science and Technology of China [2012DFA31760]; International Science and Technology Cooperation Project of TCM - State Administration of TCM, China [1601500000027 (11)]
第一作者机构：[1]Evidence-based Medicine and Clinical research Service Group, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China[2]Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China[3]The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China
通讯作者：
通讯机构：[2]Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China[3]The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China[4]China-Australia International Research Centre for Chinese Medicine, School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia
推荐引用方式(GB/T 7714)：
Feng Mei,Lu Jingmin,May Brian H.,et al.Chinese herbal medicine for patients with vascular cognitive impairment no dementia: protocol for a systematic review[J].BMJ OPEN.2016,6(3):doi:10.1136/bmjopen-2015-010295.
APA：
Feng, Mei,Lu, Jingmin,May, Brian H.,Liu, Shaonan,Guo, Xinfeng...&Lu, Chuanjian.(2016).Chinese herbal medicine for patients with vascular cognitive impairment no dementia: protocol for a systematic review.BMJ OPEN,6,(3)
MLA：
Feng, Mei,et al."Chinese herbal medicine for patients with vascular cognitive impairment no dementia: protocol for a systematic review".BMJ OPEN 6..3(2016)
