Quantitative Study of Liver Magnetic Resonance Spectroscopy Quality at 3T Using Body and Phased Array Coils with Physical Analysis and Clinical Evaluation
机构：[1]Department of Radiology, Guangdong Provincial Traditional Chinese Medicine Hospital & postdoctoral mobile research station of Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong Province, People’s Republic of China,大德路总院影像科大德路总院放射科广东省中医院[2]Biomedical Engineering School of the Southern Medical University, Guangzhou, Guangdong Province, People’s Republic of China,[3]Department of Radiology, Guangdong General Hospital, Guangzhou, Guangdong Province, People’s Republic of China,广东省人民医院[4]Bernard and Irene Schwartz Center for Biomedical Imaging, New York University School of Medicine, New York, New York, United States of America
This study aims to investigate the quality difference of short echo time (TE) breathhold 1H magnetic resonance spectroscopy (MRS) of the liver at 3.0T using the body and phased array coils, respectively. In total, 20 pairs of single-voxel proton spectra of the liver were acquired at 3.0T using the phased array and body coils as receivers. Consecutive stacks of breathhold spectra were acquired using the point resolved spectroscopy (PRESS) technique at a short TE of 30 ms and a repetition time (TR) of 1500 ms. The first spectroscopy sequence was "copied" for the second acquisition to ensure identical voxel positioning. The MRS prescan adjustments of shimming and water suppression, signal-to noise ratio (SNR), and major liver quantitative information were compared between paired spectra. Theoretical calculation of the SNR and homogeneity of the region of interest (ROI, 2 cmx2 cmx2 cm) using different coils loaded with 3D liver electromagnetic model of real human body was implemented in the theoretical analysis. The theoretical analysis showed that, inside the ROI, the SNR of the phase array coil was 2.8387 times larger than that of body coil and the homogeneity of the phase array coil and body coil was 80.10% and 93.86%, respectively. The experimental results showed excellent correlations between the paired data (all r > 0.86). Compared with the body coil group, the phased array group had slightly worse shimming effect and better SNR (all P values <.01). The discrepancy of the line width because of the different coils was approximately 0.8 Hz (0.00625 ppm). No significant differences of the major liver quantitative information of Cho/Lip2 height, Cho/Lip2 area, and lipid content were observed (all P values > 0.05). The theoretical analysis and clinical experiment showed that the phased array coil was superior to the body coil with respect to 3.0T breathhold hepatic proton MRS.
基金：
National Natural Science Foundation of China [61172034]; Science Foundation of Guangdong Province for Dr. Startup Project [S2012040006618]; Science and Technology Program of Guangzhou, China [2014J4100160]
第一作者机构：[1]Department of Radiology, Guangdong Provincial Traditional Chinese Medicine Hospital & postdoctoral mobile research station of Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong Province, People’s Republic of China,
通讯作者：
通讯机构：[2]Biomedical Engineering School of the Southern Medical University, Guangzhou, Guangdong Province, People’s Republic of China,[4]Bernard and Irene Schwartz Center for Biomedical Imaging, New York University School of Medicine, New York, New York, United States of America
推荐引用方式(GB/T 7714)：
Li Xu,Shiyong Gu,Qianjin Feng,et al.Quantitative Study of Liver Magnetic Resonance Spectroscopy Quality at 3T Using Body and Phased Array Coils with Physical Analysis and Clinical Evaluation[J].PLOS ONE.2015,10(4):doi:10.1371/journal.pone.0122999.
APA：
Li Xu,Shiyong Gu,Qianjin Feng,Changhong Liang&Sherman Xuegang Xin.(2015).Quantitative Study of Liver Magnetic Resonance Spectroscopy Quality at 3T Using Body and Phased Array Coils with Physical Analysis and Clinical Evaluation.PLOS ONE,10,(4)
MLA：
Li Xu,et al."Quantitative Study of Liver Magnetic Resonance Spectroscopy Quality at 3T Using Body and Phased Array Coils with Physical Analysis and Clinical Evaluation".PLOS ONE 10..4(2015)
