机构:[1]The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510405, China 广东省中医院深圳市中医院深圳医学信息中心[2]Department of Nephropathy Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China 大德路总院肾内科大德路总院肾内科广东省中医院[3]Outcome Assessment Branch, Department of Clinical Epidemiology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China 广东省中医院[4]Department of Nephrology laboratory, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China大德路总院肾内科大德路总院肾内科广东省中医院
Objective. To assess the efficacy and safety of Chinese medicinal herbs for Childhood Pneumonia. Methods. We included randomized controlled trials (RCTs). The searched electronic databases included PubMed, the Cochrane Central Register of Controlled Trials, EMBASE, CBM, CNKI, and VIP. All studies includedwere assessed for quality and risk bias. ReviewManager 5.1.6 software was used for data analyses, and the GRADEprofiler software was applied to classify the systematic review results. Results. Fourteen studies were identified (n = 1.824). Chinese herbs may increase total effective rate (risk ratio (RR) 1.18; 95% confidence interval (CI), 1.11-1.26) and improve cough (totalmean difference (MD), -2.18; 95% CI, (-2.66)-(-1.71)), fever (totalMD, -1.85; 95% CI, (-2.29)-(-1.40)), rales (totalMD, -1.53; 95% CI, (-1.84)-(-1.23)), and chest films (total MD, -3.10; 95% CI, (-4.11)-(-2.08)) in Childhood Pneumonia. Chinese herbs may shorten the length of hospital stay (total MD, -3.00; 95% CI, (-3.52)-(-2.48)), but no significant difference for adverse effects (RR, 0.39; 95% CI, 0.09-1.72) was identified. Conclusion. Chinese herbs may increase total effective rate and improve symptoms and signs. However, large, properly randomized, placebo-controlled, double-blind studies are required.
基金:
Scientific Research Project of Public Welfare Industry; State Administration of Traditional Chinese Medicine of China [200707004]
第一作者机构:[1]The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510405, China [2]Department of Nephropathy Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China
通讯作者:
推荐引用方式(GB/T 7714):
Yang Qianchun,Wu Darong,Mao Wei,et al.Chinese Medicinal Herbs for Childhood Pneumonia: A Systematic Review of Effectiveness and Safety[J].EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE.2013,2013:doi:10.1155/2013/203845.
APA:
Yang, Qianchun,Wu, Darong,Mao, Wei,Liu, Xusheng,Bao, Kun...&Li, Chuang.(2013).Chinese Medicinal Herbs for Childhood Pneumonia: A Systematic Review of Effectiveness and Safety.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2013,
MLA:
Yang, Qianchun,et al."Chinese Medicinal Herbs for Childhood Pneumonia: A Systematic Review of Effectiveness and Safety".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2013.(2013)