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Chinese Medicinal Herbs for Childhood Pneumonia: A Systematic Review of Effectiveness and Safety

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机构: [1]The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510405, China [2]Department of Nephropathy Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China [3]Outcome Assessment Branch, Department of Clinical Epidemiology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China [4]Department of Nephrology laboratory, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China
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Objective. To assess the efficacy and safety of Chinese medicinal herbs for Childhood Pneumonia. Methods. We included randomized controlled trials (RCTs). The searched electronic databases included PubMed, the Cochrane Central Register of Controlled Trials, EMBASE, CBM, CNKI, and VIP. All studies includedwere assessed for quality and risk bias. ReviewManager 5.1.6 software was used for data analyses, and the GRADEprofiler software was applied to classify the systematic review results. Results. Fourteen studies were identified (n = 1.824). Chinese herbs may increase total effective rate (risk ratio (RR) 1.18; 95% confidence interval (CI), 1.11-1.26) and improve cough (totalmean difference (MD), -2.18; 95% CI, (-2.66)-(-1.71)), fever (totalMD, -1.85; 95% CI, (-2.29)-(-1.40)), rales (totalMD, -1.53; 95% CI, (-1.84)-(-1.23)), and chest films (total MD, -3.10; 95% CI, (-4.11)-(-2.08)) in Childhood Pneumonia. Chinese herbs may shorten the length of hospital stay (total MD, -3.00; 95% CI, (-3.52)-(-2.48)), but no significant difference for adverse effects (RR, 0.39; 95% CI, 0.09-1.72) was identified. Conclusion. Chinese herbs may increase total effective rate and improve symptoms and signs. However, large, properly randomized, placebo-controlled, double-blind studies are required.

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基金编号: 200707004

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出版当年[2012]版:
大类 | 3 区 医学
小类 | 2 区 全科医学与补充医学
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Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE
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第一作者机构: [1]The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510405, China [2]Department of Nephropathy Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China
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