机构：[1]Department of Neurology, First People’s Hospital of Lianyungang City, Lianyungang, China[2]Institute for Biomedicine, Anhui Medical University, Hefei, China[3]Department of Pharmacy, Peking University First Hospital, Beijing, China[4]Department of Neurology, Guangdong Traditional Chinese Medicine Hospital, Guangzhou, China广东省中医院[5]Department of Cardiology, Second Hospital of Lianyungang City, Lianyungang, China[6]Institute of Nephrology, Southern Medical University, Guangzhou, China[7]School of Health Administration, Anhui Medical University, Hefei China[8]Lianyungang Center for Advanced Research in Cardiovascular Diseases, Lianyungang, China[9]Center on the Early Life Origins of Disease, Johns Hopkins University Bloomberg School of Public Health, Department of Population, Family and Reproductive Health, Baltimore, Maryland[10]Department of Cardiology, Peking University First Hospital, Beijing, China.
We aimed to examine the prevalence of lower-extremity peripheral artery disease (LE-PAD) and its associated factors in 3,128 Chinese hypertensive adults 45 to 75 years old without known cardiovascular disease, PAD, chronic kidney disease, diabetes, and dyslipidemia. A cross-sectional investigation was carried out in a rural area of Lianyungang, China. An ankle-brachial index <= 0.90 in either leg was used to define LE-PAD. Prevalence of LE-PAD was 9.0% (10.0% in women and 7.4% in men). In the multivariable logistic regression model, odds ratios (95% confidence interval) of having LE-PAD, were 1.82 (1.27 to 2.61) for participants 65 to 75 versus 45 to 55 years old, 1.48 (1.00 to 1.20) for participants with a waist circumference >= 90 versus < 90 cm, 1.47 (1.05 to 2.04) and 1.62 (1.15 to 2.27) for participants with grade 2 and 3 hypertension versus controlled blood pressure or grade 1 hypertension, 1.35 (1.00 to 1.83) and 1.61 (1.16 to 2.23) for participants with heart rate at rest 70 to 80 and >= 80 versus < 70 beats/min, and 1.41 (1.00 to 1.97) for participants with poor versus good sleeping quality. For other risk factors, gender-related differences were observed. Adjusted odds ratios of having LE-PAD for men and women were 1.07 (0.66 to 1.74) and 0.65 (0.47 to 0.90) for inland versus coastal residents and 1.03 (0.57 to 1.86) and 1.62 (1.09 to 2.41) for participants with body mass index >= 25 versus < 25 kg/m(2). In conclusion, there was a high prevalence of LE-PAD in Chinese hypertensive adults without known cardiovascular disease, PAD, chronic kidney disease, diabetes, and dyslipidemia, particularly in women in coastal areas and in participants with higher heart rate and poor sleeping quality. Therefore, ankle-brachial index determinations should be encouraged in clinical practice in Chinese hypertensive adults. (c) 2012 Elsevier Inc. All rights reserved. (Am J Cardiol 2012;110:1692-1698)
基金：
Ministry of Science and Technology, China [2012zx09101-105]; Major State Basic Research Development Program of China (973 program)National Basic Research Program of China [2012CB517703]; Department of Development and Reform, Shenzhen, Guangdong, China [(2010)1744]; Department of Science, industry, Trade and Information Technology, Shenzhen, Guangdong, China
第一作者机构：[1]Department of Neurology, First People’s Hospital of Lianyungang City, Lianyungang, China
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通讯作者：
推荐引用方式(GB/T 7714)：
He Mingli,Qin Xianhui,Cui Yimin,et al.Prevalence of Unrecognized Lower Extremity Peripheral Arterial Disease and the Associated Factors in Chinese Hypertensive Adults[J].AMERICAN JOURNAL OF CARDIOLOGY.2012,110(11):1692-1698.doi:10.1016/j.amjcard.2012.07.038.
APA：
He, Mingli,Qin, Xianhui,Cui, Yimin,Cai, Yefeng,Sun, Liming...&Huo, Yong.(2012).Prevalence of Unrecognized Lower Extremity Peripheral Arterial Disease and the Associated Factors in Chinese Hypertensive Adults.AMERICAN JOURNAL OF CARDIOLOGY,110,(11)
MLA：
He, Mingli,et al."Prevalence of Unrecognized Lower Extremity Peripheral Arterial Disease and the Associated Factors in Chinese Hypertensive Adults".AMERICAN JOURNAL OF CARDIOLOGY 110..11(2012):1692-1698
医学