机构:[1]Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China, 510120广东省中医院[2]School of Information Technology, Guangzhou University of Chinese Medicine, China, 510405深圳市中医院深圳医学信息中心[3]Faculty of Automation, GuangDong University of Technology, Guangzhou, China, 510006
Local learning is a special learning framework that considers training samples located in a small region concentric of the query sample. In many applications the concept label of query sample can be evaluated effectively only by similar training samples, such as the famous K-nearest neighbors (KNN) classifier. The metric of locality or similarity is essential in local learning, which is often application oriented and implied in local geometry of input space. In this paper, we propose to apply local learning to the task of outcome assessment and evaluation on acupuncture for cervical spondylosis (CS) in a multi-center clinical trial. The analytic data are measures of three questionnaires which are recognized tools for subjective patient-reported outcomes (PROs) evaluation. We propose a similarity evaluation method based on both Euclidean distance and the therapy effect of recent records. A Non-Dominated Sort (NDS) based methods is applied to obtain a ranking of therapy effect. A WEKA implementation decision tree classifier is applied as the main learner in our work, with comparison to two base line methods. The result shows that the proposed local learning method dramatically outperforms the global version in both classification accuracy and computational costs.
基金:
Eleventh Five-year Project of State Ministry of Science and Technology [2006BAI12B04-1]; National Basic Research Program of China (973 Program)National Basic Research Program of China [2010CB530500, 2010CB530503]; Scientific Project from Guangdong Provincial Administration of Science and Technology [2006B50107006, 2008B030301206]; research grant of Guangdong Provincial Administration of Health [C2009025]; Open Research Fund of Zhejiang First-foremost Key Subject-Acupuncture Moxibustion [ZTK2010B04]; Research grant of Guangdong Administration of Chinese Medicine [2010144]; Creative Foundation of Guangzhou University of Chinese Medicine [10CX24]; Guangdong College Student Creative Experiment Project [1184510037]
基金编号:973 Program
语种:
外文
WOS:
第一作者:
第一作者机构:[1]Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China, 510120
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推荐引用方式(GB/T 7714):
Di Zhong,Zhang Hong-Lai,Zhang Gang,et al.A Clinical Outcome Evaluation Model with Local Sample Selection: a Study on Efficacy of Acupuncture for Cervical Spondylosis[J].2011 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE WORKSHOPS.2011,829-833.doi:10.1109/BIBMW.2011.6112480.
APA:
Di, Zhong,Zhang, Hong-Lai,Zhang, Gang,Liang, Zhao-Hui,Jiang, Li...&Fu, Wen-Bin.(2011).A Clinical Outcome Evaluation Model with Local Sample Selection: a Study on Efficacy of Acupuncture for Cervical Spondylosis.2011 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE WORKSHOPS,,
MLA:
Di, Zhong,et al."A Clinical Outcome Evaluation Model with Local Sample Selection: a Study on Efficacy of Acupuncture for Cervical Spondylosis".2011 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE WORKSHOPS .(2011):829-833