机构：[1]Discipline of Chinese Medicine, School of Health Sciences, RMIT University, Bundoora, VIC 3083, Australia[2]Division of Clinical Epidemiology, Guangdong Provincial Hospital of Chinese Medicine, Guangdong 510120, China广东省中医院[3]Department of Respiratory Medicine, Box Hill Hospital and Monash University, Box Hill, VIC 3128, Australia[4]Department of Respiratory and Sleep Medicine, Austin Hospital, Heidelberg, VIC 3081, Australia[5]National DME Training Center, Guangzhou University of Chinese Medicine, Guangdong 510405, China深圳市中医院深圳医学信息中心
Ginseng alone or combined with other herbs has been increasingly used for chronic obstructive pulmonary disease (COPD). This review aims to evaluate the effectiveness and safety of oral Ginseng formulae for stable COPD. Four English databases and three Chinese databases were searched to identify randomized controlled trials. Methodological quality was assessed by Cochrane risk of bias and Jadad's scale. Data were analyzed using Review Manager 5.0. Twelve studies overall of low quality, involving 1560 participants were included. Results of three studies showed a mean difference (MD) of 0.30 (95%CI 0.02 to 0.58) for forced expiratory volume in 1 s (FEV1) improvement of Ginseng formulae versus placebo control. Findings of three studies revealed an MD of 9.43 (95%CI 3.64 to 15.21) of FEV1 % predicted between Ginseng formulae and placebo control. Quality of life (Qol) measured by St. George's Respiratory Questionnaire was improved (MD -10.32, 95%CI -14.99 to -5.65) with Ginseng formulae plus pharmacotherapy versus pharmacotherapy alone in one study. There were no severe adverse events reported. Ginseng formulae for stable COPD patients show promising evidence of lung functions and Qol improvement. However, the degree of benefit is uncertain due to potential risk of bias of the included studies. (C) 2010 Elsevier Ltd. All rights reserved.
基金：
RMIT University, Australia; National Health & Medical Research CouncilNational Health and Medical Research Council of Australia [616609]; National Institute of Complementary Medicine, Australia; Guangdong Provincial Academy of Chinese Medical Sciences, Guangdong Provincial Hospital of Chinese Medicine, China
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2010]版：
大类|3 区医学
小类|3 区心脏和心血管系统3 区呼吸系统
最新[2025]版：
大类|3 区医学
小类|3 区心脏和心血管系统3 区呼吸系统
JCR分区：
出版当年[2009]版：
Q2CARDIAC & CARDIOVASCULAR SYSTEMSQ2RESPIRATORY SYSTEM
最新[2023]版：
Q2CARDIAC & CARDIOVASCULAR SYSTEMSQ2RESPIRATORY SYSTEM
第一作者机构：[1]Discipline of Chinese Medicine, School of Health Sciences, RMIT University, Bundoora, VIC 3083, Australia
通讯作者：
通讯机构：[1]Discipline of Chinese Medicine, School of Health Sciences, RMIT University, Bundoora, VIC 3083, Australia[*1]Traditional & Complementary Medicine Research Program, Health Innovations Research Institute, and Discipline of Chinese Medicine, School of Health Sciences, RMIT University, PO Box 71, Bundoora, VIC 3083, Australia
推荐引用方式(GB/T 7714)：
An Xuedong,Zhang Anthony Lin,Yang Angela Weihong,et al.Oral ginseng formulae for stable chronic obstructive pulmonary disease: A systematic review[J].RESPIRATORY MEDICINE.2011,105(2):165-176.doi:10.1016/j.rmed.2010.11.007.
APA：
An, Xuedong,Zhang, Anthony Lin,Yang, Angela Weihong,Lin, Lin,Wu, Darong...&Xue, Charlie Changli.(2011).Oral ginseng formulae for stable chronic obstructive pulmonary disease: A systematic review.RESPIRATORY MEDICINE,105,(2)
MLA：
An, Xuedong,et al."Oral ginseng formulae for stable chronic obstructive pulmonary disease: A systematic review".RESPIRATORY MEDICINE 105..2(2011):165-176
