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Efficacy of traditional Chinese Medicine for gastric precancerous lesion: A meta-analysis of randomized controlled trials.

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机构: [1]Gastroenterology Department, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China [2]Institute of Gastroenterology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
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To evaluate efficacy of traditional Chinese medicine (TCM) for gastric precancerous lesion (GPL). Literature retrieval was conducted in seven databases from their inception through Dec. 24th, 2018. The Cochrane collaboration, Review Manager (RevMan5.3) and GRADE profiler software were conducted for this meta-analysis. In primary outcomes, results of meta-analysis showed that TCM had superior to current routine pharmacotherapy (RP) in clinical efficacy, Helicobacter pylori (Hp) eradication rate, efficacy under endoscopy, and TCM syndrome efficacy. Meanwhile, no potential publication bias was detected by Begg's and Egger's tests. In secondary outcomes, compared with control groups, experimental groups were more positive effects on improvement of stomach distention, stomachache, and heartburn. Our findings indicated that TCM could have positive effects on GPL. However, further standardized RCTs of rigorous design should be required to obtain more forceful evidence. Copyright © 2019 Elsevier Ltd. All rights reserved.

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出版当年[2019]版:
大类 | 4 区 医学
小类 | 4 区 全科医学与补充医学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 全科医学与补充医学
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第一作者机构: [1]Gastroenterology Department, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
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