详情页 - 广东省中医院知识库

当前位置：首页 > 详情页

Establishment and Verification of Synchronous Metastatic Nomogram for Gastrointestinal Stromal Tumors (GISTs): A Population-Based Analysis.

11| 认领 | 导出 | 链接全文 |

文献详情

资源类型：

WOS体系：

Pubmed体系：

收录情况： ◇ SCIE

作者：

机构： [1]Department of Gastrointestinal Surgery, Xiangya Hospital, Central South University, Changsha, China [2]Department of General Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany [3]State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macao, China [4]Department of Rheumatology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences,Guangzhou, China [5]Department of Thoracic Surgery, Fujian Provincial Hospital, Fuzhou, China [6]Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences,Hunan Normal University, Changsha, China [7]Department of Neurosurgery, Second Affiliated Hospital of Hunan Normal University, Changsha, China [8]Hunan Provincial Key Laboratory of Neurorestoration, Changsha, China

出处：

DOI：

ISSN：

摘要：

Assess the risk of synchronous metastasis and establish a nomogram in patients with GISTs. Surveillance, Epidemiology and End Results database (2004-2014) was accessed. With the logistic regression model as the basis, a nomogram was constructed. 7,256 target patients were contained in our study. The nomogram discrimination for mGIST prediction revealed that tumor size contributed most to synchronous metastasis, followed by lymph nodes, extension, pathologic grade, tumor location, and mitotic count. C-index values of predictions were 0.821 (95% CI, 0.805-0.836) and 0.815 (95% CI, 0.800-0.831), and Brier score were 0.109 and 0.112 in training and validation group, respectively. The value of area under the ROCs were 0.813 (p < 0.001) in the primary cohort and 0.819 (p < 0.001) in the validation cohort. Through the calibration curves (as seen in the figures), nomogram prediction proved to have excellent agreement with actual metastatic diseases. A new nomogram was created that can evaluate synchronous metastatic diseases in patients with GISTs. Copyright © 2020 Yuqiang Li et al.

基金：

语种：

被引次数：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2019]版：

大类 | 4 区医学

小类 | 4 区胃肠肝病学

最新[2025]版：

大类 | 4 区医学

小类 | 4 区胃肠肝病学

JCR分区：

出版当年[2018]版：

Q4 GASTROENTEROLOGY & HEPATOLOGY

最新[2023]版：

Q3 GASTROENTEROLOGY & HEPATOLOGY

影响因子： 2 最新[2023版] 2 最新五年平均 1.825 出版当年[2018版] 1.951 出版当年五年平均 1.859 出版前一年[2017版] 1.806 出版后一年[2019版]

第一作者：

第一作者机构： [1]Department of Gastrointestinal Surgery, Xiangya Hospital, Central South University, Changsha, China [2]Department of General Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

共同第一作者：

通讯作者：

通讯机构： [6]Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences,Hunan Normal University, Changsha, China [7]Department of Neurosurgery, Second Affiliated Hospital of Hunan Normal University, Changsha, China [8]Hunan Provincial Key Laboratory of Neurorestoration, Changsha, China

推荐引用方式(GB/T 7714)：

APA：

MLA：