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The role of satellite glial cells in orofacial pain.

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机构： [1]Guangdong Provincial Key Laboratory of Stomatology, Institute of Stomatological Research, Sun Yat-sen University, Guangzhou, China. [2]Department of Anesthesiology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, China. [3]The Public Service Platform of South China Sea for R&D Marine Biomedicine Resources, Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang, China. [4]Department of Rheumatology, Chinese Medicine Hospital in Linyi City, Shandong, China.

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Some chronic pain conditions in the orofacial region are common, the mechanisms underlying which are unresolved. Satellite glial cells (SGCs) are the glial cells of the peripheral nervous system. In the sensory ganglia, each neuronal body is surrounded by SGCs forming distinct functional units. The unique structural organization enables SGCs to communicate with each other and with their enwrapped neurons via a variety of ways. There is a growing body of evidence that SGCs can influence the level of neuronal excitability and are involved in the development and/or maintenance of pain. The aim of this review was to summarize the latest advances made about the implication of SGCs in orofacial pain. It may offer new targets for the development of orofacial pain treatment. © 2018 Wiley Periodicals, Inc.

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出版当年[2018]版：

大类 | 3 区医学

小类 | 4 区神经科学

最新[2025]版：

大类 | 4 区医学

小类 | 4 区神经科学

第一作者：

第一作者机构： [1]Guangdong Provincial Key Laboratory of Stomatology, Institute of Stomatological Research, Sun Yat-sen University, Guangzhou, China. [2]Department of Anesthesiology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, China.

通讯作者：

通讯机构： [1]Guangdong Provincial Key Laboratory of Stomatology, Institute of Stomatological Research, Sun Yat-sen University, Guangzhou, China. [*1]Guanghua School of Stomatology, Sun Yat‐sen University, No. 74 Zhongshan Rd 2, Guangzhou, 510080, China.

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