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The Underlying Regulated Mechanisms of Adipose Differentiation and Apoptosis of Breast Cells after Weaning.

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机构: [1]College of PIWEI institute, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China [2]Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China [3]Administration of Sports of Guangdong Province, Guangzhou, Guangdong, 510105, China [4]The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, 510080, China [5]State Key Laboratory of Ophthalmology, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510405, China [6]College of Animal Science and Technology, Yunnan Agricultural University, Kunming, Yunan, 650201, China􀀁
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关键词: Adipose tissue after weaning mammary gland adipose differentiation C/EBP ADD1/SREBP1

摘要:
Numerous experimental studies have demonstrated that a series of remodeling processes occurred in the adipose tissue during the weaning, such as differentiation. Fibroblasts in the breast at weaning stage could re-differentiate into mature adipocytes. Many transcriptional factors were involved in these processes, especially the PPARγ, C/EBP, and SREBP1. There is cell apoptosis participating in the breast tissue degeneration and secretory epithelial cells loss during weaning. In addition, hormones, especially the estrogen and pituitary hormone, play a vital role in the whole reproductive processes. In this review, we mainly focus on the underlying regulated mechanisms of differentiation of adipose tissue and apoptosis of breast cell to provide a specific insight into the physiological changes during weaning. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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中科院(CAS)分区:
出版当年[2018]版
大类 | 3 区 生物
小类 | 4 区 生化与分子生物学
最新[2025]版
大类 | 4 区 生物学
小类 | 4 区 生化与分子生物学
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出版当年[2017]版:
Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY
最新[2023]版:
Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2017版] 出版当年五年平均 出版前一年[2016版] 出版后一年[2018版]

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第一作者机构: [1]College of PIWEI institute, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China
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通讯机构: [1]College of PIWEI institute, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China [2]Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China [6]College of Animal Science and Technology, Yunnan Agricultural University, Kunming, Yunan, 650201, China􀀁 [*1]the College of PIWEI institute, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China [*2]Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510405, China [*3]College of Animal Science and Technology, Yunnan Agricultural University, Kunming, Yunan 650201, China [*4]College of PIWEI institute, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China
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