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Role of Exosomes in Photodynamic Anticancer Therapy.

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机构: [1]Key Laboratory of Molecular Target and Clinical Pharmacology, State Key Laboratory of Respiratory Disease, School of Pharmaceutical Science & Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 511436, China [2]Department of Rehabilitation Medicine, the First Affiliated Hospital of Chengdu Medical College, Chengdu 610500, China [3]Division of Chinese Medicine, School of Professional and Continuing Education, The University of Hong Kong, Hong Kong [4]Shenzhen Maternity and Child Health Care Hospital, Shenzhen 518017, China [5]Department of Biomedical Engineering, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 511436, China
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Photodynamic therapy (PDT) is a promising alternative treatment for malignancies basing on photochemical reaction induced by photosensitizers (PS) under light irradiation. Recent studies show that PDT caused abundant release of exosomes from tumor tissues. It is well-known that exosomes as carriers play an important role in cell-cell communication through transporting many kinds of bioactive molecules (e.g. lipids, proteins, mRNA, miRNA and lncRNA). Therefore, to explore the role of exosomes in photodynamic anticancer therapy has been attracting extensive attention. In the present paper, we will briefly introduce the basic principle of PDT and exosomes, and focus on discussing the role of exosomes in photodynamic anticancer therapy, to further enrich and boost the development of PDT. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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出版当年[2019]版
大类 | 3 区 医学
小类 | 3 区 生化与分子生物学 3 区 药物化学 3 区 药学
最新[2025]版
大类 | 4 区 医学
小类 | 4 区 生化与分子生物学 4 区 药物化学 4 区 药学
第一作者:
第一作者机构: [1]Key Laboratory of Molecular Target and Clinical Pharmacology, State Key Laboratory of Respiratory Disease, School of Pharmaceutical Science & Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 511436, China [2]Department of Rehabilitation Medicine, the First Affiliated Hospital of Chengdu Medical College, Chengdu 610500, China
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