机构:[1]Guangdong Provincial Key Laboratory of Optical Information Materials and Technology and Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006,[2]National Center for International Research on Green Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006,[3]Department of Radiology, The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong 510405, China深圳市中医院深圳医学信息中心
Cancer has become one of the primary causes of death worldwide. Current cancer-therapy schemes are progressing relatively slowly in terms of reducing mortality, prolonging survival, time and enhancing cure rate, owing to the enormous obstacles of cancer pathophysiology. Therefore, specific diagnosis and therapy for malignant tumors are becoming more and more crucial and urgent, especially for early cancer diagnosis and cancer-targeted therapy. Derived theranostics that combine several functions into one "package" could further overcome undesirable differences in biodistribution and selectivity between distinct imaging and therapeutic agents. In this article, we discuss a chief clinical diagnosis tool - MRI - focusing on recent progress in magnetic agents or systems in multifunctional polymer nanoassemblies for combing cancer theranostics. We describe abundant polymeric MRI-contrast agents integrated with chemotherapy, gene therapy, thermotherapy, and radiotherapy, as well as other developing directions.
基金:
This work was financially supported by Guangdong Provincial
Key Laboratory of Optical Information Materials and
Technology (grant 2017B030301007), the Special Fund on
Public Interest Research and Capacity Building in Guangdong
Province (2015A020211024), the Natural Science Foundation
of China (No. 51773069), the Guangdong Innovative Research
Team Program (2013C102), MOE International Laboratory
for Optical Information Technologies, and the 111 Project.
语种:
外文
PubmedID:
中科院(CAS)分区:
出版当年[2017]版:
大类|2 区工程技术
小类|2 区药学3 区纳米科技
最新[2025]版:
大类|2 区医学
小类|2 区药学3 区纳米科技
第一作者:
第一作者机构:[1]Guangdong Provincial Key Laboratory of Optical Information Materials and Technology and Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006,[2]National Center for International Research on Green Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006,
共同第一作者:
通讯作者:
通讯机构:[1]Guangdong Provincial Key Laboratory of Optical Information Materials and Technology and Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006,[2]National Center for International Research on Green Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006,[*1]No. 378, West Waihuan Road, Bld. 5, SCNU, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong 510006, China
推荐引用方式(GB/T 7714):
Shenglong Gan,Yisheng Lin,Yancong Feng,et al.Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics.[J].International journal of nanomedicine.2018,13:4263-4281.doi:10.2147/IJN.S164817.
APA:
Shenglong Gan,Yisheng Lin,Yancong Feng,Lingling Shui,Hao Li&Guofu Zhou.(2018).Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics..International journal of nanomedicine,13,
MLA:
Shenglong Gan,et al."Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics.".International journal of nanomedicine 13.(2018):4263-4281