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Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics.

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机构: [1]Guangdong Provincial Key Laboratory of Optical Information Materials and Technology and Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006, [2]National Center for International Research on Green Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006, [3]Department of Radiology, The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong 510405, China
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关键词: polymer nanoassembly magnetic resonance imaging cancer theranostics

摘要:
Cancer has become one of the primary causes of death worldwide. Current cancer-therapy schemes are progressing relatively slowly in terms of reducing mortality, prolonging survival, time and enhancing cure rate, owing to the enormous obstacles of cancer pathophysiology. Therefore, specific diagnosis and therapy for malignant tumors are becoming more and more crucial and urgent, especially for early cancer diagnosis and cancer-targeted therapy. Derived theranostics that combine several functions into one "package" could further overcome undesirable differences in biodistribution and selectivity between distinct imaging and therapeutic agents. In this article, we discuss a chief clinical diagnosis tool - MRI - focusing on recent progress in magnetic agents or systems in multifunctional polymer nanoassemblies for combing cancer theranostics. We describe abundant polymeric MRI-contrast agents integrated with chemotherapy, gene therapy, thermotherapy, and radiotherapy, as well as other developing directions.

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出版当年[2017]版:
大类 | 2 区 工程技术
小类 | 2 区 药学 3 区 纳米科技
最新[2025]版:
大类 | 2 区 医学
小类 | 2 区 药学 3 区 纳米科技
第一作者:
第一作者机构: [1]Guangdong Provincial Key Laboratory of Optical Information Materials and Technology and Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006, [2]National Center for International Research on Green Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006,
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通讯机构: [1]Guangdong Provincial Key Laboratory of Optical Information Materials and Technology and Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006, [2]National Center for International Research on Green Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006, [*1]No. 378, West Waihuan Road, Bld. 5, SCNU, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong 510006, China
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