机构:[1]Department of Integrated Traditional Chinese and Western Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan (410000), China[2]Department of Cardiology, Baoan Hospital of Traditional Chinese Medicine, Shenzhen, Guangdong Province (518000), China深圳市康宁医院深圳医学信息中心[3]Zhangmuba Army Sanatoriums of Hunan Military Region, Changsha, Hunan (410000), China
To investigate the effect of Chinese medicine (CM) on survival of patients with stage II and III colorectal cancer (CRC).
A total of 295 patients who received chemotherapy were assigned to Group 1. The other 171 patients received the same chemotherapy treatment combined with the usage of CM Jianpi Jiedu Formula (, JPJD) for more than 3 months (Group 2). Patients' survival time, relapse and metastasis, and cause of death were observed. Cox proportional hazard regression models were established for the analysis of the effect of independent factors on the survival prognosis of patients with CRC.
The survival rate of patients in Group 2 was higher than that of Group 1 (P<0.05). Compared with Group 1, the mean survival time was prolonged by 5.594 months and the median survival time was prolonged by 6 months in Group 2 (P=0.004). Cox regression analysis indicated that CM combined with chemotherapy provided signifificant protective effect, as observed with the improvements in the survival rates of CRC patients (P<0.01).
CM can improve the survival rate in patients with stage II and III CRC.
第一作者机构:[1]Department of Integrated Traditional Chinese and Western Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan (410000), China[2]Department of Cardiology, Baoan Hospital of Traditional Chinese Medicine, Shenzhen, Guangdong Province (518000), China
通讯作者:
推荐引用方式(GB/T 7714):
LIN Feng-xia,TIAN Li-feng,LEI Cai-yun,et al.Chinese medicine for outcomes in colorectal cancer patients: A retrospective clinical study.[J].CHINESE JOURNAL OF INTEGRATIVE MEDICINE.2017,23(9):648-653.doi:10.1007/s11655-016-2581-3.
APA:
LIN Feng-xia,TIAN Li-feng,LEI Cai-yun,DING Chen-chen,SHI Li&ZHANG Si-fang.(2017).Chinese medicine for outcomes in colorectal cancer patients: A retrospective clinical study..CHINESE JOURNAL OF INTEGRATIVE MEDICINE,23,(9)
MLA:
LIN Feng-xia,et al."Chinese medicine for outcomes in colorectal cancer patients: A retrospective clinical study.".CHINESE JOURNAL OF INTEGRATIVE MEDICINE 23..9(2017):648-653