机构：[1]Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China[2]School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China.[3]Endocrinology Department, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China[4]Department of Rheumatic Diseases, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou 510405, China深圳市中医院深圳医学信息中心
To explore the effects of traditional Chinese medicine constitution (TCMC) on transformation of good health status to suboptimal health status (SHS), we conducted a nested case-control study among college students in China. During the 18-month mean follow-up time, 543 cases of SHS (42.7%) occurred in 1273 healthy students. There was a significant (P = 0.000) and marked reduction in SHMS V1.0 total score in the case group at the 18-month follow-up (69.32 ± 5.45) compared with baseline (78.60 ± 4.70), but there was no significant change in the control group. Conditional logistic regression analysis showed that respondents reporting Yin-deficiency and Qi-deficiency were, respectively, 2.247 and 2.198 times more likely to develop SHS, while tendency to Yin-deficiency and tendency to Damp-heat were, respectively, 1.642 and 1.506 times more likely to develop SHS. However, the Balanced Constitution was a significant protective factor (OR 0.649; P < 0.05). Altogether, these findings demonstrate that Yin-deficiency, Qi-deficiency, tendency to Yin-deficiency, and tendency to Damp-heat appeared to induce a change in health status to SHS, while the Balanced Constitution seemed to restrain this change. We conclude that regulating the unbalanced TCMC (such as Yin-deficiency and Qi-deficiency) may prevent a healthy status developing into SHS or lead to the regression of SHS.
基金：
NSFC-Guangdong Joint Fund (no. U1132001),
National Science Foundation of China (nos. 81173146,
81202622, 81373707, and 81403447), Natural Science Foundation
of Guangdong Province, China (nos. 2014A030313292
and 2014A030310072), Guangdong Provincial Department
of Science and Technology and Guangdong Provincial
Academy of Traditional Chinese Medicine Joint Fund (nos.
2011B032200004, 2012A032500004, and 2013A032500008),
Guangdong Provincial Department of Science and Technology
Fund (no. 2011B031700018), China Postdoctoral Science
Foundation (no. 2014 M552187), and Science & Technical
Plan of Guangzhou, Guangdong, China (no. 2014Y2-00504).
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2014]版：
大类|3 区医学
小类|2 区全科医学与补充医学
最新[2025]版：
无
第一作者：
第一作者机构：[1]Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China[2]School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China.
共同第一作者：
通讯作者：
通讯机构：[1]Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China[2]School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China.
推荐引用方式(GB/T 7714)：
Wang Tian,Chen Jieyu,Sun Xiaomin,et al.Effects of TCMC on Transformation of Good Health Status to Suboptimal Health Status: A Nested Case-Control Study.[J].Evidence-based complementary and alternative medicine : eCAM.2015,2015:259727.doi:10.1155/2015/259727.
APA：
Wang Tian,Chen Jieyu,Sun Xiaomin,Xiang Lei,Zhou Lin...&Zhao Xiaoshan.(2015).Effects of TCMC on Transformation of Good Health Status to Suboptimal Health Status: A Nested Case-Control Study..Evidence-based complementary and alternative medicine : eCAM,2015,
MLA：
Wang Tian,et al."Effects of TCMC on Transformation of Good Health Status to Suboptimal Health Status: A Nested Case-Control Study.".Evidence-based complementary and alternative medicine : eCAM 2015.(2015):259727
