机构：[1]Department of Rehabilitation, Baoan Hospital, Southern Medical University, Shenzhen, Guangdong Province, China南方医科大学深圳医院深圳市康宁医院深圳医学信息中心[2]Department of Acupuncture and Moxibustion, First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China[3]Department of Imaging, Baoan Hospital, Southern Medical University, Shenzhen, Guangdong Province, China南方医科大学深圳医院深圳市康宁医院深圳医学信息中心[4]School of Chinese Medicine, Hong Kong Baptist University, Hong Kong Special Administrative Region, China[5]College of Acupuncture and Moxibustion, Guangxi University of Traditional Chinese Medicine, Nanning, Guangxi Zhuang Autonomous Region, China
Our previous findings have demonstrated that acupuncture at the Taixi (KI3) acupoint in healthy youths can activate neurons in cognitive-related cerebral cortex. Here, we investigated whether acupuncture at this acupoint in elderly patients with mild cognitive impairment can also activate neurons in these regions. Resting state and task-related functional magnetic resonance imaging showed that the pinprick senstation of acupuncture at the Taixi acupoint differed significantly between elderly patients with mild cognitive impairment and healthy elderly controls. Results showed that 20 brain regions were activated in both groups of participants, including the bilateral anterior cingulate gyrus (Brodmann areas [BA] 32, 24), left medial frontal cortex (BA 9, 10, 11), left cuneus (BA 19), left middle frontal gyrus (BA 11), left lingual gyrus (BA 18), right medial frontal gyrus (BA 11), bilateral inferior frontal gyrus (BA 47), left superior frontal gyrus (BA11), right cuneus (BA 19, 18), right superior temporal gyrus (BA 38), left subcallosal gyrus (BA 47), bilateral precuneus (BA 19), right medial frontal gyrus (BA 10), right superior frontal (BA 11), left cingulate gyrus (BA 32), left precentral gyrus (BA 6), and right fusiform gyrus (BA 19). These results suggest that acupuncture at the Taixi acupoint in elderly patients with mild cognitive impairment can also activate some brain regions.
基金：
National Natural Science Foundation of China, No.
81173354; the Natural Science Foundation of Guangdong Province, No. 10451810101005862; a
grant from Guangdong Administration of Traditional Chinese Medicine, No. 20111032, 20132019;
the Science and Technology Plan Project of Baoan District, Shenzhen City, No. 200902159.
第一作者机构：[1]Department of Rehabilitation, Baoan Hospital, Southern Medical University, Shenzhen, Guangdong Province, China[2]Department of Acupuncture and Moxibustion, First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China
通讯作者：
通讯机构：[5]College of Acupuncture and Moxibustion, Guangxi University of Traditional Chinese Medicine, Nanning, Guangxi Zhuang Autonomous Region, China[*1]College of Acupuncture and Moxibustion, Guangxi University of Traditional Chinese Medicine, Nanning, Guangxi Zhuang Autonomous Region, China
推荐引用方式(GB/T 7714)：
Chen Shangjie,Xu Maosheng,Li Hong,et al.Acupuncture at the Taixi (KI3) acupoint activates cerebral neurons in elderly patients with mild cognitive impairment.[J].NEURAL REGENERATION RESEARCH.2014,9(11):1163-1168.doi:10.4103/1673-5374.135319.
APA：
Chen Shangjie,Xu Maosheng,Li Hong,Liang Jiuping,Yin Liang...&Zhao Lihua.(2014).Acupuncture at the Taixi (KI3) acupoint activates cerebral neurons in elderly patients with mild cognitive impairment..NEURAL REGENERATION RESEARCH,9,(11)
MLA：
Chen Shangjie,et al."Acupuncture at the Taixi (KI3) acupoint activates cerebral neurons in elderly patients with mild cognitive impairment.".NEURAL REGENERATION RESEARCH 9..11(2014):1163-1168
