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Chinese herbal medicine liu jun zi tang and xiang sha liu jun zi tang for functional dyspepsia: meta-analysis of randomized controlled trials.

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机构: [1]Department of Traditional Chinese Medicine, Southern Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangdong, Guangzhou 510515, China [2]School of Traditional Chinese Medicine, Southern Medical University, 1838 North Guangzhou Avenue, Guangdong, Guangzhou 510515, China [3]Department of Science and Technology, Southern Medical University, 1838 North Guangzhou Avenue, Guangdong, Guangzhou 510515, China
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Objectives. To assess the efficacy and safety of Liu Jun Zi Tang (LJZT) and Xiang Sha Liu Jun Zi Tang (XSLJZT) for treating functional dyspepsia. Methods. Literature searches were carried out on Medline database, Cochrane Library, CNKI database, Chinese Biomedical Literature database, Wanfang database, and VIP database up to July 2012. Hand search for further references was conducted. Study selection, data extraction, quality assessment, and data analyses were performed according to the Cochrane standards. Results. Fifteen publications in total were suitable for inclusion. There was evidence that LJZT compared with prokinetic drugs increased symptom improvement (odds ratio 1.96, 95% CI 1.15 to 3.36). There was also evidence that XSLJZT compared with prokinetic drugs increased symptom improvement (odds ratio 2.63, 95% CI 1.72 to 4.03). No adverse events were reported in LJZT or XSLJZT group in any of these randomized controlled trials. Conclusion. LJZT and XSLJZT might be more effective compared with prokinetic drugs in the treatment of functional dyspepsia, and no side effects are identified in the included trials. However, due to poor methodological quality in the majority of included studies, the potential benefit from LJZT and XSLJZT need to be confirmed in rigorously designed, multicentre, and large-scale trials.

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出版当年[2011]版:
大类 | 3 区 医学
小类 | 2 区 全科医学与补充医学
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第一作者机构: [1]Department of Traditional Chinese Medicine, Southern Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangdong, Guangzhou 510515, China [2]School of Traditional Chinese Medicine, Southern Medical University, 1838 North Guangzhou Avenue, Guangdong, Guangzhou 510515, China
通讯作者:
通讯机构: [1]Department of Traditional Chinese Medicine, Southern Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangdong, Guangzhou 510515, China [2]School of Traditional Chinese Medicine, Southern Medical University, 1838 North Guangzhou Avenue, Guangdong, Guangzhou 510515, China
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