机构：[1]The Second Clinical Medical School, Guangzhou University of Chinese Medicine,广东省中医院[2]Department of Emergency, the Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,大德路总院急诊科大德路总院急诊科广东省中医院[3]The First Clinical Medical School, Guangzhou University of Chinese Medicine,[4]Department of Critical Care Medicine, Beijing University of Chinese Medicine Shenzhen Hospital, Shenzhen, Guangdong, Province, China.北京大学深圳医院深圳市康宁医院深圳医学信息中心
Coronary heart disease (CHD) is the leading cause of morbidity and mortality worldwide. Guipi Decoction (GPD) is a classical traditional Chinese medication used to treat CHD. However, systematic review and meta-analysis regarding its efficacy and safety has not been systematically evaluated. The objective of this protocol is to determine the efficacy and safety of GPD in the treatment of CHD.
Randomized controlled trials evaluating the effectiveness and safety of GPD in the treatment of CHD will be retrieved from 8 electronic databases, including PubMed, EMBASE, Cochrane Library, Web of science, China National Knowledge Infrastructure Database, VIP Database, Wanfang Database and China Biology Medicine Database. Study selection, data collection, risk of bias assessment, and evaluation of the quality of evidence will be performed in order. Data will be analyzed by RevMan V.5.3.5 software.
This study will evaluate the efficacy and safety of GPD in the treatment of CHD.
This systematic review will provide evidence for determining whether or not GPD is an effective and safe intervention for CHD.
PROSPERO CRD 42020156420.
基金：
This work is supported by National Natural Science Foundation of China (No. 81273961 to BC)
第一作者机构：[1]The Second Clinical Medical School, Guangzhou University of Chinese Medicine,[2]Department of Emergency, the Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,
通讯作者：
通讯机构：[1]The Second Clinical Medical School, Guangzhou University of Chinese Medicine,[2]Department of Emergency, the Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,[*1]Department of Emergency, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, 55 Neihuanxi Road, Panyu District, Guangzhou, Guangdong Province, China
推荐引用方式(GB/T 7714)：
Gao Huanjia,Liu Shiyu,Cai Hairong,et al.Guipi decoction for coronary heart disease A protocol for a systematic review and meta-analysis[J].MEDICINE.2020,99(32):doi:10.1097/MD.0000000000021589.
APA：
Gao Huanjia,Liu Shiyu,Cai Hairong,Chen Dongjie,Fu Xue...&Chen Bojun.(2020).Guipi decoction for coronary heart disease A protocol for a systematic review and meta-analysis.MEDICINE,99,(32)
MLA：
Gao Huanjia,et al."Guipi decoction for coronary heart disease A protocol for a systematic review and meta-analysis".MEDICINE 99..32(2020)
