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Chinese Herbal Medicines for Promoting Blood Circulation and Removing Blood Stasis for Preventing Deep Venous Thrombosis after Total Hip Arthroplasty: A Systematic Review and Meta-Analysis

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机构: [1]Second School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, P.R. China [2]Department of Orthopaedics, Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou 510120, P.R. China
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关键词: Promoting Blood Circulation and Removing Blood Stasis (PBCRBSM) traditional Chinese medicine compound Total Hip Arthroplasty (THA) Deep Vein Thrombosis (DVT) meta-analysis RevMan 5 3 software

摘要:
To evaluate the efficacy and safety of Chinese herbal medicines for promoting blood circulation and removing blood stasis (PBCRBSM) in preventing deep venous thrombosis (DVT) after total hip arthroplasty (THA). The Databases were searched for studies comparing the preventive abilities of PBCRBSM and Western medicine, such as low molecular weight heparin (LMWH), rivaroxaban, and aspirin, as well as for randomized controlled trials on DVT after THA. Data were analyzed using RevMan 5.3 software. A total of 3254 randomized controlled trials were included, including 1630 cases in the experimental group and 1624 cases in the control group. Meta-analysis showed that compared with Western medicine, PBCRBSM reduced the incidence of DVT (OR=0.38, 95% CI [0.30, 0.48], P < 0.001); prolonged activated partial thromboplastin time (APTT) (SMD=0.44, 95% CI [0.35, 0.53], P < 0.001); reduced D-dimer (SMD=-0.75, 95% CI [-0.84,-0.65], P < 0.001), FIB (SMD=-0.61, 95% CI [-0.72, -0.50], P < 0.001), blood viscosity (P<0.01), circumference difference in lower extremities (P<0.01), venous blood flow velocity (SMD=0.97, 95% CI [0.77, 1.16], P < 0.001), and drainage volume (SMD=-1.53, 95% CI [-1.71, -1.35], P < 0.001); and reduced adverse reactions (OR = 0.32, 95% CI [0.19, 0.56], P < 0.001). There was no significant difference in prolonging prothrombin time (PT) between traditional Chinese medicine and Western medicine (SMD = 0.07, 95% CI [-0.0.01). 3, 0.16], P > 0.05. PBCRBSM is an effective method for preventing DVT after THA and has fewer adverse effects. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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基金编号: 2014

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出版当年[2020]版:
大类 | 4 区 医学
小类 | 4 区 生化研究方法 4 区 应用化学 4 区 药学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 生化研究方法 4 区 应用化学 4 区 药学
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出版当年[2019]版:
Q3 CHEMISTRY, APPLIED Q4 BIOCHEMICAL RESEARCH METHODS Q4 PHARMACOLOGY & PHARMACY
最新[2023]版:
Q3 CHEMISTRY, APPLIED Q3 PHARMACOLOGY & PHARMACY Q4 BIOCHEMICAL RESEARCH METHODS

影响因子: 最新[2023版] 最新五年平均 出版当年[2019版] 出版当年五年平均 出版前一年[2018版] 出版后一年[2020版]

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第一作者机构: [1]Second School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, P.R. China
通讯作者:
通讯机构: [2]Department of Orthopaedics, Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou 510120, P.R. China [*1]Department of Orthopaedics, Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou 510120, P.R. China
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