Psoriasis vulgaris is a chronic skin condition estimated to affect 2-4% of the population globally. It is characterised by sharply marginated patches of papules and plaques covered with silvery scales, and is often accompanied by itching (pruritus) and pain. Psoriasis often occurs in the teenage years, and is more prevalent in younger females. Psoriasis has a significant impact on quality of life due to physical appearance and time required to treat lesions and maintain clothing and bedding. The economic cost of psoriasis is substantial, including direct costs of management and indirect costs due to loss of productivity. Management in conventional medicine is determined by the severity of the disease, with topical agents used for mild disease and systemic agents used for severe disease. This chapter describes the risk factors for psoriasis, pathological process, diagnosis and severity assessment, and pharmacological and non-pharmacological management.