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Reference Values of Carotid Ultrafast Pulse-Wave Velocity: A Prospective, Multicenter, Population-Based Study

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机构: [1]Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China [2]Department of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu 610072, Sichuan Province, China [3]Health Medical Department, Dalian Municipal Central Hospital, Dalian, 116033, Liaoning Province, China [4]Department of Ultrasound, The Third People’s Hospital of Zhengzhou, Zhengzhou 450000, Henan Province, China [5]Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China [6]Department of Ultrasound Diagnosis, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China [7]Department of Ultrasound, Affiliated Hospital of Yan'an University, Yan'an 716000, Shanxi Province, China [8]Ultrasound Department, Central Hospital of Chongqing Three Gorges, Chongqing 404000, China [9]Medical Technology Department, Guangdong Second Traditional Chinese Medicine Hospital, Guangzhou 510060, Guangdong Province, China [10]Department of Ultrasound, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China [11]Ultrasonic Department, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, Guangdong Province, China [12]Department of Cardiac Ultrasound, The Fourth Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China [13]Department of Ultrasound, Xinxiang Central Hospital, Xinxiang 453000, Henan province, China [14]Department of Ultrasound, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi Province, China [15]Ultrasonic Medicine, The First Affiliated Hospital of Bengbu Medical College, Bengbu 233000, Anhui Province, China [16]Ultrasonography Department, Henan Provincial People’s Hospital, Zhengzhou 450003, Henan Province, China [17]Department of Medical Ultrasound, The Central Hospital of Wuhan, Wuhan 430000, Hubei Province, China [18]Department of Ultrasound, Hebei General Hospital, Shijiazhuang 050000, Hebei Province, China [19]Department of Ultrasound, The Fourth Affiliated Hospital of China Medical University, Shenyang 110032, Liaoning Province, China [20]Department of Medical Ultrasound, Geriatric Hospital of Nanjing Medical University&Jiangsu Provincial Geriatric Hospital, Nanjing 210024, Jiangsu Province, China [21]Ultrasonography Department, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150000, Heilongjiang Province, China [22]Department of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China [23]Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China.
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关键词: Ultrafast ultrasound imaging pulse wave velocity reference value Chinese adults

摘要:
Ultrafast ultrasound imaging has been demonstrated to be an effective method to evaluate carotid stiffness through carotid pulse wave velocity (PWV) with high reproducibility, but lack of reference values has precluded its widespread use in clinical practice. This study aimed to establish reference values of PWV for ultrafast ultrasound imaging in a prospective, multicenter, population-based cohort study and to investigate the main determinants of carotid PWV. A total of 1,544 healthy Han Chinese volunteers (581 [38%] men; age, 18-95 years) were enrolled from 32 collaborating laboratories in China. The participants were categorized by age, blood pressure (BP), and body mass index (BMI). The basic clinical parameters and the carotid PWV at the beginning of systole (BS) and end of systole (ES) were measured via ultrafast ultrasound imaging techniques. The PWV at both BS and ES was significantly higher in the left carotid artery than in the right carotid artery. The PWV at BS was significantly higher in men than in women; however, no significant difference was noted in the PWV at ES between men and women. Multiple linear regression analyses revealed that age, BP, and BMI were independently correlated with the PWV at both BS and ES. The PWV at BS and ES progressively increased with increase in age, BP, and BMI. Further, the age- and sex-specific reference values of carotid PWV for ultrafast ultrasound imaging were established. Reference values of carotid PWV for ultrafast ultrasound imaging, stratified by sex and age, were determined for the first time. Age, BP, and BMI were the dominant determinants of carotid PWV for ultrafast ultrasound imaging, which should be considered in clinical practice for assessing arterial stiffness. Copyright © 2021. Published by Elsevier Inc.

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出版当年[2020]版:
大类 | 2 区 医学
小类 | 2 区 心脏和心血管系统
最新[2025]版:
大类 | 1 区 医学
小类 | 2 区 心脏和心血管系统
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出版当年[2019]版:
Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
最新[2023]版:
Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

影响因子: 最新[2023版] 最新五年平均 出版当年[2019版] 出版当年五年平均 出版前一年[2018版] 出版后一年[2020版]

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第一作者机构: [1]Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China [*3]Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
通讯作者:
通讯机构: [1]Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China [2]Department of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu 610072, Sichuan Province, China [23]Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China. [*1]Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China [*2]Department of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu 610072, Sichuan Province, China [*3]Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
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