机构：[1]College of Chemistry, Fuzhou University, Fuzhou 350116, China[2]State Key Laboratory of Structural Chemistry and Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, Center for Excellence in Molecular Synthesis, Fujian Institute of Research on the Structure of Matter, University of Chinese Academy of Sciences, Fuzhou 350100, China[3]Orthopedics Department, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, China[4]Pingxiang University, Pingxiang 337055, China
N-Heterocyclic carbene-catalyzed asymmetric construction of cyclopentenones using enals and α-diketones is achieved, furnishing a series of highly functionalized cyclopentenones in a highly diastereo- and enantioselective manner. The protocol tolerates substrates with both aromatic and aliphatic groups, and further transformations of the products delivered a range of value-added molecules.
基金：
NSFC (21871260 and
22071242), the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB20000000), and the
Science and Technology Research Program of the Education
Department of Jiangxi Province (GJJ1991151).
第一作者机构：[1]College of Chemistry, Fuzhou University, Fuzhou 350116, China
通讯作者：
通讯机构：[*1]College of Chemistry, Fuzhou University, Fuzhou 350116, China[*2]State Key Laboratory of Structural Chemistry and Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, Center for Excellence in Molecular Synthesis, Fujian Institute of Research on the Structure of Matter, University of Chinese Academy of Sciences, Fuzhou 350100, China[*3]Orthopedics Department, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, China
化学