Eczema is a common non-communicable skin disease that has been around us for a long time. While the current protocols for treating eczema only focus on the part of the skin, the mostly used corticosteroids and palliative medications are often resulting in numerous side effects. Traditional Chinese Medicine (TCM) can therefore provide an alternative treatment for the disease, using the novel approach of the Liver-Skin axis relationship. Here we provide a case of an 11-year old girl who was treated using TCM with clearing liver and detoxing. With the use of a renowned TCM prescription, Long Dan Xie Gan Tang, chronic eczema was successfully controlled and even completely cured. In the present study, our clinical evidence was also complementary to the preceding clinic of Chinese Society; we suggest a novel therapy for eczema on reducing heat and detoxing of the liver by 'liver-skin axis' for the first time, which may play positive roles in treating eczema patients. Copyright (C) 2013 - All Rights Reserved - Pharmacophore