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A Case of AB Para-Bombay Phenotype with Weak A Antigen Expression

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机构: [1]Guangzhou Univ Chinese Med, Dept Blood Transfus, Affiliated Hosp 2, 111 Dade Rd, Guangzhou 510120, Guangdong, Peoples R China [2]Guangdong Acad Med Sci, Dept Guangdong Ctr Clin Lab, Guangdong Prov Peoples Hosp, Guangzhou, Peoples R China
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关键词: para-Bombay phenotype Lewis blood group secretor gene sequencing

摘要:
Background: The para-Bombay phenotype is characterized by H antigen partially or totally deficient on red blood cells and the presence of ABH substances in body fluids. Methods: A patient with discrepant results in forward and reverse ABO phenotyping was further investigated by serological and molecular methods. Results: Ortho gel and tube results showed weak A antigen expression and weak antibody reacting with A and B cells. Absorption-elution assay detected B antigen, and saliva test confirmed substances H were present. The patient was confirmed as A102B101 and Le(a+b+) phenotype. Conclusions: These findings suggest that the case is AB Para-Bombay Phenotype (secretor).

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基金编号: 2020-KT1137

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出版当年[2020]版:
大类 | 4 区 医学
小类 | 4 区 医学实验技术
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 医学实验技术
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出版当年[2019]版:
Q4 MEDICAL LABORATORY TECHNOLOGY
最新[2023]版:
Q4 MEDICAL LABORATORY TECHNOLOGY

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第一作者机构: [1]Guangzhou Univ Chinese Med, Dept Blood Transfus, Affiliated Hosp 2, 111 Dade Rd, Guangzhou 510120, Guangdong, Peoples R China
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