机构：[1]Department of Acupuncture and Moxibustion, Quzhou Hospital of Traditional Chinese Medicine, Quzhou, China[2]The Second Clinical Medical School, Guangzhou University of Chinese Medicine, Guangzhou, China广东省中医院[3]Department of Clinical Laboratory Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China[4]School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China[5]Department of Acupuncture and Moxibustion, Nanfang Hospital, Southern Medical University, Guangzhou, China
Background. Studies on serum uric acid (sUA) levels and hypertension (HTN) are controversial. To investigate the association between the sUA level and the incident of HTN in middle-aged and elderly adults, we performed this study. Methods. 6399 participants aged >= 40 years from the National Health and Nutrition Examination Survey (NHANES) were included. Weighted multiple logistic regression analysis was carried out to evaluate the relationship between the sUA level and the incident of HTN, exploring the potential nonlinear relationship using the fitted smoothing curves. If nonlinearity was observed, the inflection point was further calculated by a recursive algorithm. Results. A positive relationship between the sUA level and the incident of HTN was found. However, it may differ in different race groups, nor between male and female. Moreover, the association between the sUA level and the incident of HTN followed a U-shaped curve in male (turning point: sUA 4.1 mg/dL) and Whites (turning point: sUA 7.9 mg/dL). Conclusions. The results revealed that the sUA level is positively correlated with the incident of HTN, in middle-aged and elderly adults. However, it followed a U-shaped curve in males and Whites.</p>
第一作者机构：[1]Department of Acupuncture and Moxibustion, Quzhou Hospital of Traditional Chinese Medicine, Quzhou, China
通讯作者：
通讯机构：[4]School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China[5]Department of Acupuncture and Moxibustion, Nanfang Hospital, Southern Medical University, Guangzhou, China
推荐引用方式(GB/T 7714)：
Xu Xianpeng,Huang Jinke,Wu Simin,et al.The Association between the Serum Uric Acid Level and Hypertension in Middle-Aged and Elderly Adults[J].CARDIOVASCULAR THERAPEUTICS.2021,2021:doi:10.1155/2021/4626062.
APA：
Xu, Xianpeng,Huang, Jinke,Wu, Simin,Ji, Qingjie,Guo, Xuguang&Huang, Yong.(2021).The Association between the Serum Uric Acid Level and Hypertension in Middle-Aged and Elderly Adults.CARDIOVASCULAR THERAPEUTICS,2021,
MLA：
Xu, Xianpeng,et al."The Association between the Serum Uric Acid Level and Hypertension in Middle-Aged and Elderly Adults".CARDIOVASCULAR THERAPEUTICS 2021.(2021)
