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Rehabilitation effect of rTMS combined with cognitive training on cognitive impairment after traumatic brain injury.

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收录情况： ◇ SCIE ◇ 预警期刊

作者：
Zhou Li[1,*1] * ; Huang Xuming[1] ; Li Haiyan[2] ; Guo Ruomi[3] ; Wang Jihui[2] ; Zhang Yu[4] ; Lu Zhengqi[2] ;
机构： [1]Department of Rehabilitation, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou,Guangdong Province, China [2]Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China [3]Department of Radiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China [4]Department of Pathology, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, Guangdong Province, China
出处：
ISSN：

关键词： Cognitive impairment after traumatic brain injury multimodal magnetic resonance imaging cognitive training rehabilitation effect

摘要：
To innvestigate the rehabilitation effects of repetitive transcranial magnetic stimulation (rTMS) combined with cognitive training on cognitive impairment in patients with traumatic brain injury (TBI) by using multimodal magnetic resonance imaging.Clinical data of 166 patients with cognitive impairment after TBI were retrospectively analyzed. The patients were assigned into an observation group and a control group according to different treatment methods, with 83 cases in each group. The observation group was given rTMS + cognitive training, and the control group was given cognitive training only. The changes in GCS score, the Cho/Cr, Cho/NAA and NAA/Cr ratios examined by MRSI, the score of cognitive impairment, the grading of cognitive impairment, and the changes in modified Barthel index were observed and compared between the two groups.The GCS score, and the ratios of Cho/Cr, Cho/NAA and NAA/Cr after treatment were better than those before treatment in both groups and were lower in the observation group compared with the control group (all P<0.05). The score and grading of cognitive impairment as well as modified Barthel index after treatment were all significantly better in the observation group than in the control group (all P<0.05).rTMS can improve the rehabilitation effect on cognitive impairment in patients after TBI and is recommended for clinical use.AJTR Copyright © 2021.

基金：
This work was supported by the Youth Science Foundation Projects of National Nature Science Foundation of China for the Molecular mechanism of high-frequency rTMS in reduction cortical neurons apoptosis by activating the Wnt/ Ca2+/PKC Signaling Pathway via NRF1 transcriptional regulation in Alzheimer’s disease (82002388).
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外文
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中科院(CAS)分区：
出版当年[2020]版：
大类 | 3 区 医学
小类 | 3 区 医学：研究与实验 3 区 肿瘤学
最新[2025]版：
大类 | 4 区 医学
小类 | 4 区 医学：研究与实验 4 区 肿瘤学
JCR分区：
出版当年[2019]版：
Q2 MEDICINE, RESEARCH & EXPERIMENTAL Q2 ONCOLOGY
最新[2023]版：
Q3 MEDICINE, RESEARCH & EXPERIMENTAL Q4 ONCOLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2019版] 出版当年五年平均 出版前一年[2018版] 出版后一年[2020版]

第一作者：
第一作者机构： [1]Department of Rehabilitation, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou,Guangdong Province, China [*1]Department of Rehabilitation, The First Affiliated Hospital of Guangdong Pharmaceutical University, No. 19 Nonglinxia Road, Guangzhou 510080, Guangdong Province, China
通讯作者：
通讯机构： [1]Department of Rehabilitation, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou,Guangdong Province, China [*1]Department of Rehabilitation, The First Affiliated Hospital of Guangdong Pharmaceutical University, No. 19 Nonglinxia Road, Guangzhou 510080, Guangdong Province, China
推荐引用方式(GB/T 7714)：
Zhou Li,Huang Xuming,Li Haiyan,et al.Rehabilitation effect of rTMS combined with cognitive training on cognitive impairment after traumatic brain injury.[J].AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH.2021,13(10):11711-11717.
APA：
Zhou Li,Huang Xuming,Li Haiyan,Guo Ruomi,Wang Jihui...&Lu Zhengqi.(2021).Rehabilitation effect of rTMS combined with cognitive training on cognitive impairment after traumatic brain injury..AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH,13,(10)
MLA：
Zhou Li,et al."Rehabilitation effect of rTMS combined with cognitive training on cognitive impairment after traumatic brain injury.".AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH 13..10(2021):11711-11717

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