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Instability of Hyperthermia Temperature for Magnetic Nanoparticles of Low Anisotropy Constant Due to Nonlinear Characteristics.

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机构: [1]School of Mechanical and Electrical Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, Guangdong, China. [2]Department of Emergency Medicine, Mackay Memorial Hospital, Taipei 10449, Taiwan, R.O.C. [3]Department of Chinese Medicine, Buddhist Dalin Tzu Chi General Hospital, Chiayi 622, Taiwan, R.O.C. [4]Department of Mechanical Engineering, Cheng Shiu University, Kaohsiung 833, Taiwan, R.O.C. [5]Department of Mechanical and Electrical Engineering, Dongguan Polytechnic, Dongguan 523808, Guangdong, China.
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Magnetic nanoparticles (MNPs) subjected to external alternating magnetic field can induce heat in MNPs due to hysteresis, which is usually employed for tumor hyperthermia. An effective hyperthermia treatment should selectively kill the tumor cells without damaging the ambient healthy tissue. Hence, it is important for hyperthermia to correctly control the alternating magnetic field-induced temperature of MNPs in the tumor. This work develops a thermal model to analyze various forms of temperature-rise with time in magnetic nanoparticles for tumor hyperthermia. Results show that there are horizontal, linear rise, square root, exponential decay and abrupt temperature-rise lines with time in MNPs. The horizontal, linear rise, and square root temperature lines with time are consistent with the available experimental data. It is worthily noted that the form of abrupt temperaturerise with time can result in harm to the normal cells or tissue. If the abrupt temperature-rise does not be controlled and predicted well.

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出版当年[2020]版:
大类 | 4 区 工程技术
小类 | 4 区 化学综合 4 区 材料科学:综合 4 区 纳米科技 4 区 物理:应用 4 区 物理:凝聚态物理
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第一作者机构: [1]School of Mechanical and Electrical Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, Guangdong, China.
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