机构：[1]School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P. R. China. E-mail: blyin@scut.edu.cn [2]Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou 510006, P. R. China. E-mail: doctliu@263.net广东省中医院
A protocol for Pd-catalyzed intra-and intermolecular 2,5-alkoxyarylation reactions of furans to diastereospecifically synthesize two series of spirooxindoles is reported. This protocol likely involves an intra-molecular dearomatizing Heck-type alpha-arylation of the furan ring to produce a cyclic allylic palladium and the subsequent intra- or intermolecular introduction of an alkyloxyl group at the other alpha-position of the ring, with different facial selectivities.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21272078, 21572068]; Science and Technology Planning Project of Guangdong Province, China [2014A020221035]
第一作者机构：[1]School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P. R. China. E-mail: blyin@scut.edu.cn
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Liu Jianchao,Xu Xiaobing,Li Jiuyi,et al.Palladium-catalyzed dearomatizing 2,5-alkoxyarylation of furan rings: diastereospecific access to spirooxindoles[J].CHEMICAL COMMUNICATIONS.2016,52(61):9550-9553.doi:10.1039/c6cc04298h.
APA：
Liu, Jianchao,Xu, Xiaobing,Li, Jiuyi,Liu, Bo,Jiang, Huanfeng&Yin, Biaolin.(2016).Palladium-catalyzed dearomatizing 2,5-alkoxyarylation of furan rings: diastereospecific access to spirooxindoles.CHEMICAL COMMUNICATIONS,52,(61)
MLA：
Liu, Jianchao,et al."Palladium-catalyzed dearomatizing 2,5-alkoxyarylation of furan rings: diastereospecific access to spirooxindoles".CHEMICAL COMMUNICATIONS 52..61(2016):9550-9553
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