详情页 - 广东省中医院知识库

当前位置：首页 > 详情页

New insights of epigenetics in vascular and cellular senescence

12| 认领 | 导出 | 链接全文 |

文献详情

资源类型：

WOS体系：

Pubmed体系：

收录情况： ◇ SCIE

作者：

机构： [1]State Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy, Macau University of Science and Technology, Macau, China [2]College of Pharmacy, Guilin Medical University, Guilin, China [3]Department of Cardiovascular Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangdong Cardiovascular Institute, Guangzhou 510080, China [4]Department of Pharmacology, Shanghai Key Laboratory of Bioactive Small Molecules, School of Pharmacy, Fudan University, Shanghai 201203, China

出处：

DOI：

ISSN：

关键词： aging vascular senescence epigenetic

摘要：

Vascular senescence plays a vital role in cardiovascular diseases and it is closely related to cellular senescence. At the molecular level, aging begins with a single cell, and it is characterized by telomere shortening, mitochondrial dysfunction, stem cell exhaustion, epigenetic changes, and so on. Epigenetics is an independent discipline that modifies DNA activity without altering the DNA sequence. The application of epigenetics helps to alleviate the occurrence of human diseases, inhibit senescence, and even inhibit tumor occurrence. Epigenetics mainly includes the modification of DNA, histone, and noncoding RNA. Herein, the application of epigenetics in vascular senescence and aging has been reviewed to provide the prospects and innovative inspirations for future research.

基金：

语种：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2020]版：

大类 | 4 区医学

小类 | 4 区医学：内科

最新[2025]版：

大类 | 2 区医学

小类 | 2 区医学：内科

JCR分区：

出版当年[2019]版：

无

最新[2023]版：

Q1 MEDICINE, GENERAL & INTERNAL

影响因子： 4.7 最新[2023版] 3.8 最新五年平均 0 出版当年[2019版] 0 出版当年五年平均 0 出版前一年[2018版] 3.451 出版后一年[2020版]

第一作者：

第一作者机构： [1]State Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy, Macau University of Science and Technology, Macau, China

通讯作者：

通讯机构： [1]State Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy, Macau University of Science and Technology, Macau, China [3]Department of Cardiovascular Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangdong Cardiovascular Institute, Guangzhou 510080, China [4]Department of Pharmacology, Shanghai Key Laboratory of Bioactive Small Molecules, School of Pharmacy, Fudan University, Shanghai 201203, China [*1]State Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy, Macau University of Science and Technology, Macau, China. [*2]Department of Cardiovascular Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangdong Cardiovascular Institute, Guangzhou 510080, China.

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Discovery of deoxyandrographolide and its novel effect on vascular senescence by targeting HDAC1 [2]The transcription factor GATA6 accelerates vascular smooth muscle cell senescence-related arterial calcification by counteracting the role of anti-aging factor SIRT6 and impeding DNA damage repair [3]Female germline stem cells: aging and anti-aging [4]Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/SIRT1 pathway [5]Epigenetic regulations of cellular senescence in osteoporosis [6]Regulation of cisplatin resistance in bladder cancer by epigenetic mechanisms [7]Accelerated Kidney Aging in Diabetes Mellitus. [8]Ginsenoside Rb1 retards aging process by regulating cell cycle, apoptotic pathway and metabolism of aging mice. [9]Anti-aging activity of Radix polygoni multiflori preparata in aging mice model induced by D-galactose by bioassay method [10]Epigenetic and senescence markers indicate an accelerated ageing-like state in women with preeclamptic pregnancies.