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Safety and Efficacy of the Tong-Fu-Xing-Shen Herbal Formula for Stroke-Associated Pneumonia

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研究单位: [1]Guangdong Province Hospital of Tradtional Chinese Medicine,Guangzhou,Guangdong,China,510120 [2]People's Hospital of Ganzhou City [3]People's Hospital of Lianjiang City [4]Yangjiang Hospital of Traditional Chinese Medicine [5]Shenyang No. 2 Hospital of Traditional Chinese Medicine [6]Guangdong Provincial Hospital of Traditional Chinese Medicine

关键词: stroke-associated pneumonia Tong-Fu-Xing-Shen herbal formula Traditional Chinese medicine Brain-gut-lung axis Randomized controlled trial

研究目的:
Stroke-associated pneumonia (SAP) is the major complication of acute intracerebral haemorrhage (AICH), leads to poor clinical outcomes and increases the financial burden on the medical system. Prophylactic antibiotics do not reduce the mortality rate of SAP. The Tong-Fu-Xing-Shen herbal formula (TFXS) was shown to be effective for the prevention and treatment SAP in a previous clinical trial. To clarify whether TFXS is effective and safe for the treatment of SAP and affects the immunological mechanism of the "brain-gut-lung" pathway of SAP, the investigators designed this study.

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