Chemical investigation of the aerial part of Chonemorpha griffithii has led to the isolation of 20 compounds, comprising six lignans (1-6), six triterpenoids (7-12), four phenolic acids (13-16), two flavonoids (17 and 18), one cyclitol (19) and one aliphatic acid (20). Among them, 5'-methoxy-7'-oxomatairesinol (1) was identified to be a new lignan. It is the first report of the presence of those compounds in this genus. Two 24-methyl-29-norcycloartane triterpenoids (10 and 11) were considered as the chemotaxonomic markers for the species C griffithii. (C) 2013 Elsevier Ltd. All rights reserved.