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A Clinical Trial on Whole-brain Radiotherapy With Temozolomide Concurrent Chemotherapy or Avoidance of Hippocampus for Patients of Brain Metastases

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研究单位: [1]Sun Yat-sen University [2]Guangdong Provincial Hospital Of Chinese Medicine [3]The Affiliated Cancer Hospital Of Guangzhou Medical Collage [4]The First Affiliated Hospital Of Guangzhou Medical Collage [5]Department of Radiation Oncology,Sun Yat-Sen University Cancer Center [6]Guangdong Three Nine Brain Hospital [7]Guangzhou First People's Hospital [8]Guangzhou People's Liberation Army Hospital 421

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The purpose of this study is to evaluate the effects on neurocognitive function of whole-brain radiotherapy (WBRT) with/without TMZ concurrent chemotherapy or avoidance of hippocampus for patients of brain metastases, as well as the feasibility and risk of avoidance of hippocampus during whole-brain radiotherapy

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