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Prevalence of multiple sclerosis in Guangzhou, China: A population-based case-finding prospective study

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资源类型：
WOS体系：
Pubmed体系：

收录情况： ◇ SCIE

作者：
Liu Zifeng[1] * ; Nie Zhiqiang[2,*2] ; Lu Yaxin[1] * ; Sun Junru[3] ; Zhou Luyao[4] ; Long Youming[5] ; Wang Honghao[6] ; Feng Huiyu[7] ; Li Yi[8] ; Wang Zhanhang[9] ; Zhao Yuanqi[10] ; Du Baoxin[10] ; Guo Aihua[11] ; Qiu Wei[4,*1] ;
机构： [1]Big Data and Artificial Intelligence Center, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China [2]Department of Cardiology, Hypertension Research Laboratory, Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China [3]Medical Insurance Office, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China [4]Department of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China [5]Department of Neurology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China [6]Department of Neurology, Nanfang Hospital of Southern Medical University, Guangzhou, China [7]Department of Neurology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China [8]Department of Neurology, Sun Yat Sen Memorial Hospital of Sun Yat sen University, Guangzhou, China [9]Department of Neurology, Guangdong 999 Brain Hospital, Guangzhou, China [10]Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China [11]Department of Neurology, Guangzhou First People’s Hospital, Guangzhou, China
出处：
DOI： 10.1016/j.msard.2022.104151
ISSN：

关键词： Multiple sclerosis Prevalence Population-based Case-finding

摘要：
Multiple sclerosis (MS) is rare in China, and the prevalence previously reported may be biased. Currently, few studies that have investigated the prevalence of MS in China based on the latest diagnostic criteria.Through a population-based survey from August 8, 2021 to December 31, 2021, we calculated the prevalence of multiple sclerosis in 18,676,605 residents of Guangzhou, China. MS patients were identified through the health insurance system of the Guangzhou Health Insurance Bureau, and we surveyed 17 large tertiary hospitals using a case-finding approach. All MS patients were diagnosed according to the 2017 McDonald criteria.A total of 143 patients in the resident population of Guangzhou were diagnosed with MS, with a crude prevalence of 0.77 per 100,000 (95% confidence interval (CI): 0.65-0.90), and the prevalence was higher in in females (1.14/100,000) than in males (0.44/100,000). The age-adjusted prevalence was 0.92 per 100,000 (95% CI: 0.77-1.10). The prevalence peaked at the age of 25-29 years (2.86/100,000) for both males and females (1.44/100,000 and 4.42/100,000, respectively).This is the first study to report the prevalence of MS in Guangzhou, China, according to the criteria. Our study shows that the prevalence of MS in Guangzhou is lower than that in other cities in China.Copyright © 2022 Elsevier B.V. All rights reserved.

基金：
This work was supported by grants from the National Natural Science Foundation of China (81971140) and Guangzhou Science and Technology Plan Project (202102010263, 202102010009).
语种：
外文
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PubmedID：
中科院(CAS)分区：
出版当年[2021]版：
大类 | 3 区 医学
小类 | 4 区 临床神经病学
最新[2025]版：
大类 | 3 区 医学
小类 | 4 区 临床神经病学
JCR分区：
出版当年[2020]版：
Q2 CLINICAL NEUROLOGY
最新[2023]版：
Q2 CLINICAL NEUROLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2020版] 出版当年五年平均 出版前一年[2019版] 出版后一年[2021版]

第一作者：
第一作者机构： [1]Big Data and Artificial Intelligence Center, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
共同第一作者：
通讯作者：
通讯机构： [2]Department of Cardiology, Hypertension Research Laboratory, Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China [4]Department of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China [*1]Department of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China [*2]Department of Cardiology, Hypertension Research Laboratory, Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
推荐引用方式(GB/T 7714)：
Liu Zifeng,Nie Zhiqiang,Lu Yaxin,et al.Prevalence of multiple sclerosis in Guangzhou, China: A population-based case-finding prospective study[J].MULTIPLE SCLEROSIS AND RELATED DISORDERS.2022,68:doi:10.1016/j.msard.2022.104151.
APA：
Liu Zifeng,Nie Zhiqiang,Lu Yaxin,Sun Junru,Zhou Luyao...&Qiu Wei.(2022).Prevalence of multiple sclerosis in Guangzhou, China: A population-based case-finding prospective study.MULTIPLE SCLEROSIS AND RELATED DISORDERS,68,
MLA：
Liu Zifeng,et al."Prevalence of multiple sclerosis in Guangzhou, China: A population-based case-finding prospective study".MULTIPLE SCLEROSIS AND RELATED DISORDERS 68.(2022)

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