机构：[1]Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China,[2]The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China,广东省中医院[3]Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong SAR, China,[4]Shanghai GuangHua Hospital of Integrated Traditional Chinese and Western Medicine, Institute of Arthritis Research, Shanghai Academy of Chinese Medical Sciences, Shanghai, China
Rheumatoid arthritis (RA) is a systemic autoimmune disease accompanied with joint destruction. Serious joint destruction will eventually lead to disability and the decline of life quality in RA patients. At present, the therapeutic effect of drugs to alleviate joint destruction in RA is limited. Recently, accumulating evidences have shown that long non-coding RNAs (lncRNAs) play an important role in the pathogenesis of joint diseases. Therefore, this paper reviews the expression change and the action mechanism of lncRNAs in joint destruction of RA in recent years. A more comprehensive understanding of the role of lncRNAs in joint destruction will help the treatment of RA.
基金：
National Key Research and Development Program of China; CACMS Innovation Fund; [2018YFC1705205]; [CI 2021A01509]
第一作者机构：[1]Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China,[2]The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China,
通讯作者：
通讯机构：[3]Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong SAR, China,[4]Shanghai GuangHua Hospital of Integrated Traditional Chinese and Western Medicine, Institute of Arthritis Research, Shanghai Academy of Chinese Medical Sciences, Shanghai, China
推荐引用方式(GB/T 7714)：
Zhao Hanxiao,Li Li,Zhao Ning,et al.The effect of long non-coding RNAs in joint destruction of rheumatoid arthritis[J].FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY.2022,10:doi:10.3389/fcell.2022.1011371.
APA：
Zhao, Hanxiao,Li, Li,Zhao, Ning,Lu, Aiping,Lu, Cheng&He, Xiaojuan.(2022).The effect of long non-coding RNAs in joint destruction of rheumatoid arthritis.FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY,10,
MLA：
Zhao, Hanxiao,et al."The effect of long non-coding RNAs in joint destruction of rheumatoid arthritis".FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 10.(2022)
