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Impact of Falls Within 3 Months on the Short-Term Prognoses of Elderly Patients in Intensive Care Units: A Retrospective Cohort Study Using Stabilized Inverse Probability Treatment Weighting

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机构: [1]School of Nursing, Jinan University, Guangzhou, People's Republic of China. [2]Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China. [3]Department of Intensive Care Unit, The First Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China. [4]Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Informatization, Guangzhou, People's Republic of China.
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关键词: accidental falls older adults inverse probability treatment weighting intensive care unit

摘要:
Falls are a major public health problem in the older adults that can lead to poor clinical outcomes. There have been few reports on the short-term prognoses of older critically ill patients, and so we sought to determine the impact of falls on elderly patients in intensive care units (ICUs).This retrospective study of 4503 patients (aged 65 years or older) analyzed data in the Medical Information Mart for Intensive Care-III critical care database. Of those, 2459 (54.6%) older adults are males, and 2044 (45.4%) older adults are females. Based on information from the medical care record assessment forms, patients were classified into the following two groups based on whether they had a fall within the previous 3 months: falls (n=1142) and nonfalls (n=3361). The primary outcomes of this study were 30- and 90-day mortality. Associations between the results of the Kaplan-Meier (KM) survival analysis, Cox proportional-hazards regression models, and subgroup analysis and its outcomes were analyzed using stabilized inverse probability treatment weighting (IPTW).KM survival curves with stabilized IPTW indicated that 30- and 90-day survival rates were significantly lower in elderly critically ill patients with a history of falls within the previous 3 months than in those patients without a history of falls (all p<0.001). Multivariate Cox proportional-hazards regression analysis indicated that 30- and 90-day mortality rates were 1.35 times higher (95% confidence interval [CI]=1.16-1.57, p<0.001) and 1.36 times higher (95% CI=1.19-1.55, p<0.001), respectively, in elderly critically ill patients with a history of falls within the previous 3 months than in those patients without a history of falls.Experience of falls within the previous 3 months prior to ICU admission increased the risk of short-term mortality and affected the prognoses of elderly patients. Falls should therefore receive adequate attention from clinical healthcare providers and management decision-makers.© 2022 Cheng et al.

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出版当年[2021]版:
大类 | 3 区 医学
小类 | 3 区 老年医学
最新[2025]版:
大类 | 2 区 医学
小类 | 3 区 老年医学
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第一作者机构: [1]School of Nursing, Jinan University, Guangzhou, People's Republic of China.
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通讯机构: [2]Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China. [4]Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Informatization, Guangzhou, People's Republic of China. [*1]Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, People’s Republic of China
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