详情页 - 广东省中医院知识库

当前位置：首页 > 详情页

The Overgeneralization of Pain-Related Fear in Individuals with Higher Pain Sensitivity: A Behavioral and Event-Related Potential Study

7| 认领 | 导出 | 链接全文 |

文献详情

资源类型：

WOS体系：

Pubmed体系：

收录情况： ◇ SCIE

作者：

机构： [1]Department of Rehabilitation Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510280, China. [2]Department of Clinical Medical College of Acupuncture and Rehabilitation, University of Traditional Chinese Medicine, Guangzhou, Guangdong, 510006, China.

出处：

DOI：

ISSN：

关键词： fear generalization pain sensitivity event-related potential (ERP) attention

摘要：

Fear generalization contributes to the development and maintenance of pain. Pain sensitivity has been proposed to predict the strength of fear responses to aversive stimuli. However, whether individual variation in pain sensitivity affects pain-related fear generalization and its underlying cognitive processing remains unclear. To address this gap, we recorded behavioral and event-related potential (ERP) data among 22 high pain sensitivity (HPS) and 22 low pain sensitivity (LPS) healthy adults when exposed to a fear generalization paradigm. The behavioral results indicate that the HPS group displayed higher unconditioned stimulus expectancy and greater fear, arousal, and anxiety ratings to conditioned stimulus and generalization stimulus than the LPS group (all p values < 0.05). The ERP results showed that the HPS group exhibited a larger late positive potential evoked by GS2, GS3 and CS- (all p < 0.005) but a smaller N1 evoked by all CS and GSs (all p values < 0.05) relative to the LPS group. These findings suggest that individuals with a high level of pain sensitivity allocate more attention resources to pain-related threatening stimuli, which contributes to an overgeneralization of pain-related fear.Copyright © 2023. Published by Elsevier B.V.

基金：

语种：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2022]版：

大类 | 3 区医学

小类 | 4 区神经科学

最新[2025]版：

大类 | 4 区医学

小类 | 4 区神经科学

JCR分区：

出版当年[2021]版：

Q3 NEUROSCIENCES

最新[2023]版：

Q3 NEUROSCIENCES

影响因子： 2.7 最新[2023版] 2.9 最新五年平均 3.61 出版当年[2021版] 3.676 出版当年五年平均 3.252 出版前一年[2020版] 2.9 出版后一年[2022版]

第一作者：

第一作者机构： [1]Department of Rehabilitation Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510280, China.

共同第一作者：

通讯作者：

通讯机构： [1]Department of Rehabilitation Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510280, China. [*1]Department of Rehabilitation Medicine, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, Guangzhou 510282, China.

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Impaired orienting in youth with Internet Addiction: Evidence from the Attention Network Task (ANT) [2]Cracked Tongue Extraction Model Based on Improved U-Net Method [3]HTC-Net: Hashimoto's thyroiditis ultrasound image classification model based on residual network reinforced by channel attention mechanism [4]Interference of Illusory Contour Perception by a Distractor. [5]Altered functional connectivity among default, attention, and control networks in idiopathic generalized epilepsy. [6]Need for Greater Attention to Joint Damage in Rhupus Patients: Results from an Ultrasound Study. [7]五神脏论治注意力缺陷多动障碍 [8]Fast medical concept normalization for biomedical literature based on stack and index optimized self-attention [9]Attention guided discriminative feature learning and adaptive fusion for grading hepatocellular carcinoma with Contrast-enhanced MR. [10]Pay attention to the health problems of health care professionals: the key to fighting COVID-19.