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On-site quantitation of xanthine in fish and serum using a smartphone-based spectrophotometer integrated with a dual-readout nanosensing assay

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WOS体系：
Pubmed体系：

收录情况： ◇ SCIE

作者：
Xu Ningxia[1,6] * ; Xiao Meng[1,5] * ; Yu Zipei[1] * ; Jin Baohui[3] ; Yang Mengsu[4] ; Yi Changqing[1,2,*1] ;
机构： [1]Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instruments, Sun Yat-Sen University, Guangzhou 510275, China [2]Research Institute of Sun Yat-Sen University in Shenzhen, Shenzhen 518057, China [3]Food Inspection and Quarantine Center, Shenzhen Customs, Shenzhen 518033, China [4]Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China [5]Department of Clinical Laboratory Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong 510000, China [6]Department of Medical Equipment, Hospital of Jiangxi University of Traditional Chinese Medicine (Jiangxi Provincial Hospital of Traditional Chinese Medicine), Nanchang, Jiangxi 330000, China
出处：
DOI： 10.1016/j.foodchem.2023.137107
ISSN：

关键词： Xanthine Carbon nanodots Silver nanoparticle Inner filter effect Portable device

摘要：
Rapid and quantitative biochemical analysis at points-of-need is imperative for food safety inspection. This work reports on: 1) a stand-alone smartphone-based "two-in-one" spectrophotometer (the SAFS) installed with a self-developed application (the SAFS-App) which can precisely collect both absorption spectra and fluorescence spectra in a reproducible manner within 5 s; and 2) a straightforward protocol for xanthine detection using fluorescent carbon nanodots and silver nanoparticles. The assay performed with the SAFS demonstrates high specificity towards xanthine, and a linear range of 1-60 μM with LODs of 0.38 and 0.58 μM for colorimetric and fluorometric readouts, respectively. The reliability and robustness of the SAFS are validated by on-site quantitation of xanthine in fish and serum samples, with comparable accuracy to HPLC method. More importantly, the SAFS presents itself as an appealing device which is accessible to everyone through the Internet of Things and can be tailored for diverse point-of-care testing applications.Copyright © 2023 Elsevier Ltd. All rights reserved.

基金：
Science, Technology and Innovation Commission of Shenzhen, China (JCYJ20210324140004013 and GJHZ20210705142200001), the National Key Research and Development Program of China (2022YFE0201800), and China Postdoctoral Science Foundation (no. 2023M730745) is gratefully acknowledged.
语种：
外文
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2023]版：
大类 | 1 区 农林科学
小类 | 1 区 应用化学 1 区 食品科技 1 区 营养学
最新[2025]版：
大类 | 1 区 农林科学
小类 | 1 区 应用化学 1 区 食品科技 1 区 营养学
JCR分区：
出版当年[2022]版：
Q1 CHEMISTRY, APPLIED Q1 FOOD SCIENCE & TECHNOLOGY Q1 NUTRITION & DIETETICS
最新[2023]版：
Q1 CHEMISTRY, APPLIED Q1 FOOD SCIENCE & TECHNOLOGY Q1 NUTRITION & DIETETICS

影响因子： 最新[2023版] 最新五年平均 出版当年[2022版] 出版当年五年平均 出版前一年[2021版] 出版后一年[2023版]

第一作者：
第一作者机构： [1]Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instruments, Sun Yat-Sen University, Guangzhou 510275, China [6]Department of Medical Equipment, Hospital of Jiangxi University of Traditional Chinese Medicine (Jiangxi Provincial Hospital of Traditional Chinese Medicine), Nanchang, Jiangxi 330000, China
共同第一作者：
通讯作者：
通讯机构： [1]Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instruments, Sun Yat-Sen University, Guangzhou 510275, China [2]Research Institute of Sun Yat-Sen University in Shenzhen, Shenzhen 518057, China [*1]Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instruments, Sun Yat-Sen University, Guangzhou 510275, China.
推荐引用方式(GB/T 7714)：
Xu Ningxia,Xiao Meng,Yu Zipei,et al.On-site quantitation of xanthine in fish and serum using a smartphone-based spectrophotometer integrated with a dual-readout nanosensing assay[J].FOOD CHEMISTRY.2024,431:doi:10.1016/j.foodchem.2023.137107.
APA：
Xu Ningxia,Xiao Meng,Yu Zipei,Jin Baohui,Yang Mengsu&Yi Changqing.(2024).On-site quantitation of xanthine in fish and serum using a smartphone-based spectrophotometer integrated with a dual-readout nanosensing assay.FOOD CHEMISTRY,431,
MLA：
Xu Ningxia,et al."On-site quantitation of xanthine in fish and serum using a smartphone-based spectrophotometer integrated with a dual-readout nanosensing assay".FOOD CHEMISTRY 431.(2024)

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