Aspiration thrombectomy versus stent retriever thrombectomy as a first-line approach for cardiogenic cerebral embolism and cryptogenic stroke in large vessels of the anterior circulation
机构：[1]Guangzhou Panyu Cent Hosp, Dept Stroke Ctr, Guangzhou, Guangdong, Peoples R China[2]Zhongshan Hosp Tradit Chinese Med, Dept Neurosurg, Zhongshan, Guangdong, Peoples R China[3]Guangzhou Med Univ, Dept Intens Care Unit, Affiliated Hosp 2, Guangzhou, Guangdong, Peoples R China
Subject This study aims to compare the clinical efficacy of aspiration thrombectomy and stent retriever thrombectomy as first-line approaches for anterior circulation large vessel cardiogenic cerebral embolism and cryptogenic stroke.Method This retrospective observational study included patients with anterior circulation large vessel cardiogenic cerebral embolism and cryptogenic stroke treated with endovascular therapy. Patients were grouped according to the first-line approach they received: aspiration thrombectomy or stent retriever thrombectomy. The primary outcome measure was the change in the National Institute of Health Stroke Scale (NIHSS) score from preoperative to immediate postoperative and from preoperative to discharge. Secondary indicators included the rate of favorable prognosis at discharge [Modified Rankin Scale (mRS) score <= 2], successful vessel recanalization rate [modified Treatment in Cerebral Ischemia (mTICI) score >= 2b], time from successful femoral artery puncture to successful vessel recanalization, and perioperative complications.Result The study included 127 cases, with 1 case withdrawal after enrollment due to a stroke of another determined cause, with 83 in the aspiration thrombectomy group and 43 cases in the stent retriever thrombectomy group. The change in NIHSS score from preoperative to immediate postoperative was 5 (1, 8) in the aspiration thrombectomy group and 1 (0, 4.5) in the stent retriever thrombectomy group. The change from preoperative to discharge was 8 (5, 12) in the aspiration thrombectomy group and 4 (0, 9) in the stent retriever thrombectomy group. The aspiration thrombectomy group exhibited significantly better prognosis rates and shorter time from successful femoral artery puncture to successful vessel recanalization. There were no significant differences between the two groups in terms of successful vessel recanalization rates and perioperative complications.Conclusion As a first-line approach for anterior circulation large vessel cardiogenic cerebral embolism and cryptogenic stroke, aspiration thrombectomy leads to better improvement in neurological functional deficits and prognosis rates compared to stent retriever thrombectomy.
基金：
Panyu District Key discipline (specialty) Medical and health Project (2020-Z04-009); and The Science and Technology Program of Panyu (2022-Z04-095)
第一作者机构：[1]Guangzhou Panyu Cent Hosp, Dept Stroke Ctr, Guangzhou, Guangdong, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Peng Zhiqiang,Chen Junchen,Cao Wenying,et al.Aspiration thrombectomy versus stent retriever thrombectomy as a first-line approach for cardiogenic cerebral embolism and cryptogenic stroke in large vessels of the anterior circulation[J].FRONTIERS IN NEUROLOGY.2024,14:doi:10.3389/fneur.2023.1324725.
APA：
Peng, Zhiqiang,Chen, Junchen,Cao, Wenying,Zhao, Dongqing,Ma, Mi...&Cao, Minqi.(2024).Aspiration thrombectomy versus stent retriever thrombectomy as a first-line approach for cardiogenic cerebral embolism and cryptogenic stroke in large vessels of the anterior circulation.FRONTIERS IN NEUROLOGY,14,
MLA：
Peng, Zhiqiang,et al."Aspiration thrombectomy versus stent retriever thrombectomy as a first-line approach for cardiogenic cerebral embolism and cryptogenic stroke in large vessels of the anterior circulation".FRONTIERS IN NEUROLOGY 14.(2024)
