机构:[1]School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, P. R. China[2]Department of Pharmacy, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, P. R. China广东省中医院[3]Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, P. R. China
Phytochemical investigation of Sargassum fusiforme (Harv.) Setch. led to the discovery of fifteen secondary metabolites, including three sterols, three monoterpenes, five nitrogenous compounds, two fatty acids, and two others. Among them, two compounds are new, while the other thirteen compounds were isolated from S. fusiforme for the first time. The structures of the two new compounds were identified by NMR and HR-ESI-MS data analyses, and the absolute configurations were established by comparing the calculated and experimental ECD spectroscopic data.
基金:
Special Project for Marine Economic Development (Six Major Marine Industries) of Guangdong Province Department of Natural Resources of Guangdong Province [[2020]039]; Science and Technology Planning Project of Guangdong Province [2017A020217008, 2015A020216017]; Fire Plan Project of the Guangzhou University of Chinese Medicine [XH20170110]; NSFCNational Natural Science Foundation of China [81741160]; Natural Science Foundation of Guangdong ProvinceNational Natural Science Foundation of Guangdong Province [2014A030313411]; Open Subject of State Key Laboratory of Marine Resources Utilization in the South China Sea of Hainan University [2016003]; Open Subject of Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research