机构：[1]Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, 111 Dade Road, Guangzhou, Guangdong China 8620- 81887233大德路总院广东省中医院[2]Guangdong Pharmaceutical University, Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Guangzhou, Guangdong, China 8620-39352093[3]MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, South China Normal University, Guangzhou, Guangdong, China 8620-85211438[4]Guangzhou Jinan Biomedical Research and Development center Co., Ltd, College of Life Science and Technology, Jinan University, Guangzhou, Guangdong, China 8620-85220504
Guigan longmu Decoction(GL), take in Zhong-jing Zhang's Treatise on Exogenous of Febrile Diseases, composed of Cinnamomum cassia Presl(Guizhi), Glycyrrhiza uralensis Fisch.(Gancao), Fossil fragments(Longgu) and Oyster shell(Muli), is a traditional Chinese medicine(TCM) formula and is widely used as a clinically medication formula for its efficiency in improving sleep. But the underlying mechanisms by which it exerts therapeutic function have not been thoroughly studied. Cellular damage induced by free-radicals like reactive oxygen species has been implicated in several diseases. Hence naturally anti-oxidant play a vital role in combating these conditions. In this study, The effects of GL on free radical scavenging and anti-oxidative capacity is investigated. By free radical scavenging assays, the IC50 values of GL were 46.03 +/- 1.26, 51.45 +/- 0.74 mu g/ml with DPPH, ABTS assay respectively, and 0.611 mg ferrous sulfate/1 mg GL with FRAP assay. These results indicated that the antioxidant properties of GL hold great potential used as an alternative to more toxic synthetic anti-oxidants as an additive in food, cosmetic and pharmaceutical preparations for the oxidative diseases treatment.
基金：
Natural Science Foundation of Henan Province (182300410328), the
National Natural Science Foundation of China (U1404824), and Innovation Scientists and Technicians Troop
Construction Projects of Henan Province, the science and technology projects of Guangdong Province
(2016A040402033),Clinical Efficacy Evaluation and Development Research of Shuxin Anshen Ointment in Treating
Insomnia Guangdong Provincial Science and Technology Project(2014A020221088),Study on Anti-aging Effect of
Jianpi Yangwei Ointment and Its Development and Application Special Project for Preventive Treatment of Diseases of
Guangdong Provincial Hospital of Chinese Medicine(YN2016ZWB07),Evaluation of anti-aging effect and mechanism
of Jianpi Yangwei ointment by Caenorhabditis elegans model, Research Project of TCM Science and Technology of
Guangdong Provincial Hospital of Chinese Medicine(YN2015QN08). National Engineering Research Center For
Modernazation Of Traditional Chinese Medicine-Sub Center.
语种：
外文
WOS：
第一作者：
第一作者机构：[1]Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, 111 Dade Road, Guangzhou, Guangdong China 8620- 81887233
通讯作者：
推荐引用方式(GB/T 7714)：
Xu Fu-ping,Wu Zi-cong,Chen Tong-sheng,et al.Evaluation of free radical scavenging and anti-oxidative capacity of Guigan longmu Decoction[J].14TH NATIONAL CONFERENCE ON LASER TECHNOLOGY AND OPTOELECTRONICS (LTO 2019).2019,11170:doi:10.1117/12.2531791.
APA：
Xu, Fu-ping,Wu, Zi-cong,Chen, Tong-sheng,Wang, Yi-fei&Wang, Zhi-ping.(2019).Evaluation of free radical scavenging and anti-oxidative capacity of Guigan longmu Decoction.14TH NATIONAL CONFERENCE ON LASER TECHNOLOGY AND OPTOELECTRONICS (LTO 2019),11170,
MLA：
Xu, Fu-ping,et al."Evaluation of free radical scavenging and anti-oxidative capacity of Guigan longmu Decoction".14TH NATIONAL CONFERENCE ON LASER TECHNOLOGY AND OPTOELECTRONICS (LTO 2019) 11170.(2019)
