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Are left ventricular ejection fraction and left atrial diameter related to atrial fibrillation recurrence after catheter ablation?: A meta-analysis

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机构: [a]Second School of Clinical Medicine, Guangzhou Univ Chinese Med, [b]Department of Orthopedics, Second Affiliated Hospital of Guangzhou Univ Chinese Med (Guangdong Provincial Hospital of Chinese Medicine), [c]Beijing University of Chinese Medicine, Beijing, China, [d]Department of Cardiology, Second Affiliated Hospital of Guangzhou Univ Chinese Med (Guangdong Provincial Hospital of Chinese Medicine).
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关键词: atrial fibrillation recurrence catheter ablation left atrial diameter left ventricular ejection fraction meta-analysis

摘要:
Atrial fibrillation (AF), the most common form of arrhythmia, is associated with the prevalence of many common cardiovascular and cerebrovascular diseases. Catheter ablation is considered the first-line therapy for AF; however, AF recurrence is very common after catheter ablation. Studies have been performed to analyze the factors associated with AF recurrence, but none have reached a consistent conclusion on whether left ventricular ejection fraction (LVEF) and left atrial diameter (LA diameter) affect AF recurrence after catheter ablation.The databases PubMed, Embase, and the Cochrane Library were used to search for relevant studies up to September 2017. RevMan 5.3.5 software provided by the Cochrane Collaboration Network was used to conduct this meta-analysis.Thirteen studies involving 2825 patients were included in this meta-analysis. Overall, the results revealed that elevated LA diameter values were significantly associated with AF recurrence in patients after catheter ablation (MD=2.19, 95% CI: 1.63-2.75, P<.001), while baseline LVEF levels were not significantly positively associated with AF recurrence in patients after catheter ablation (MD=-0.91, 95% CI: -1.18 to 1.67, P=.14).Overall, elevated LA diameter may be associated with AF recurrence after catheter ablation; however, there was no direct relationship between LVEF values and AF recurrence after catheter ablation when baseline LVEF values are normal or mildly decreased. Besides, because of publication bias, further studies should be performed to explore the mechanisms underlying AF recurrence.

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基金编号: General Program, No. 81774219

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出版当年[2017]版:
大类 | 3 区 医学
小类 | 3 区 医学:内科
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 医学:内科
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出版当年[2016]版:
Q2 MEDICINE, GENERAL & INTERNAL
最新[2023]版:
Q2 MEDICINE, GENERAL & INTERNAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2016版] 出版当年五年平均 出版前一年[2015版] 出版后一年[2017版]

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第一作者机构: [a]Second School of Clinical Medicine, Guangzhou Univ Chinese Med,
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通讯机构: [a]Second School of Clinical Medicine, Guangzhou Univ Chinese Med, [c]Beijing University of Chinese Medicine, Beijing, China, [d]Department of Cardiology, Second Affiliated Hospital of Guangzhou Univ Chinese Med (Guangdong Provincial Hospital of Chinese Medicine). [*1]Second Affiliated Hospital of Guangzhou Univ Chinese Med and Beijing University of Chinese Medicine, China
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