机构:[a]Second School of Clinical Medicine, Guangzhou Univ Chinese Med,广东省中医院[b]Department of Orthopedics, Second Affiliated Hospital of Guangzhou Univ Chinese Med (Guangdong Provincial Hospital of Chinese Medicine),大德路总院骨科广东省中医院[c]Beijing University of Chinese Medicine, Beijing, China,[d]Department of Cardiology, Second Affiliated Hospital of Guangzhou Univ Chinese Med (Guangdong Provincial Hospital of Chinese Medicine).广东省中医院
Atrial fibrillation (AF), the most common form of arrhythmia, is associated with the prevalence of many common cardiovascular and cerebrovascular diseases. Catheter ablation is considered the first-line therapy for AF; however, AF recurrence is very common after catheter ablation. Studies have been performed to analyze the factors associated with AF recurrence, but none have reached a consistent conclusion on whether left ventricular ejection fraction (LVEF) and left atrial diameter (LA diameter) affect AF recurrence after catheter ablation.The databases PubMed, Embase, and the Cochrane Library were used to search for relevant studies up to September 2017. RevMan 5.3.5 software provided by the Cochrane Collaboration Network was used to conduct this meta-analysis.Thirteen studies involving 2825 patients were included in this meta-analysis. Overall, the results revealed that elevated LA diameter values were significantly associated with AF recurrence in patients after catheter ablation (MD=2.19, 95% CI: 1.63-2.75, P<.001), while baseline LVEF levels were not significantly positively associated with AF recurrence in patients after catheter ablation (MD=-0.91, 95% CI: -1.18 to 1.67, P=.14).Overall, elevated LA diameter may be associated with AF recurrence after catheter ablation; however, there was no direct relationship between LVEF values and AF recurrence after catheter ablation when baseline LVEF values are normal or mildly decreased. Besides, because of publication bias, further studies should be performed to explore the mechanisms underlying AF recurrence.
基金:
This project was funded by the National Natural Science Foundation Project (General Program, No. 81774219), Guangzhou Science and Technology Plan
Project (No. 201710010107), Joint Innovation Specific Project in Key Areas from Guangdong Branch Institute of China Academy of Chinese Medical Sciences (No.
ZZ0908065), Guangdong Medical Science and Technology Research Foundation Project (No. A2017215).
第一作者机构:[a]Second School of Clinical Medicine, Guangzhou Univ Chinese Med,
通讯作者:
通讯机构:[a]Second School of Clinical Medicine, Guangzhou Univ Chinese Med,[c]Beijing University of Chinese Medicine, Beijing, China,[d]Department of Cardiology, Second Affiliated Hospital of Guangzhou Univ Chinese Med (Guangdong Provincial Hospital of Chinese Medicine).[*1]Second Affiliated Hospital of Guangzhou Univ Chinese Med and Beijing University of Chinese Medicine, China
推荐引用方式(GB/T 7714):
Xiao Jin,Jianke Pan,Huanlin Wu,et al.Are left ventricular ejection fraction and left atrial diameter related to atrial fibrillation recurrence after catheter ablation?: A meta-analysis[J].MEDICINE.2018,97(20):doi:10.1097/MD.0000000000010822.
APA:
Xiao Jin,Jianke Pan,Huanlin Wu&Danping Xu.(2018).Are left ventricular ejection fraction and left atrial diameter related to atrial fibrillation recurrence after catheter ablation?: A meta-analysis.MEDICINE,97,(20)
MLA:
Xiao Jin,et al."Are left ventricular ejection fraction and left atrial diameter related to atrial fibrillation recurrence after catheter ablation?: A meta-analysis".MEDICINE 97..20(2018)