The new heterocycles compound N-((3R, 4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d] pyrimidin-4-amine (1), designed using 4-chloro-7H-pyrrolo[2,3-d] pyrimidine (2) as start material, was successfully obtained via multiple synthesis route and finally characterized by IR, H-1 NMR, and single crystal X-ray crystallography. In addition, in vitro anticancer activity of compound 1 on three human skin cancer cell lines (A431, SK23 and HME1) was further determined.
第一作者机构：[1]Guangzhou Univ Chinese Med, Affiliated Hosp 2, Dept Dermatol, Guangzhou, Guangdong, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Zhang Zhongzhao,Zhang Jin,Du Yiqi.A New Organic Heterocycles Compound: Crystal Structure and Anti-Cancer Activity in Skin Cancer[J].LATIN AMERICAN JOURNAL OF PHARMACY.2018,37(5):935-939.
APA：
Zhang, Zhongzhao,Zhang, Jin&Du, Yiqi.(2018).A New Organic Heterocycles Compound: Crystal Structure and Anti-Cancer Activity in Skin Cancer.LATIN AMERICAN JOURNAL OF PHARMACY,37,(5)
MLA：
Zhang, Zhongzhao,et al."A New Organic Heterocycles Compound: Crystal Structure and Anti-Cancer Activity in Skin Cancer".LATIN AMERICAN JOURNAL OF PHARMACY 37..5(2018):935-939
